Environmental enrichment produces a behavioral phenotype mediated by low cyclic adenosine monophosphate response element binding (CREB) activity in the nucleus accumbens.
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Transcriptional mechanisms of drug addictionTranscriptional and epigenetic mechanisms of addictionNatural rewards, neuroplasticity, and non-drug addictionsDrug withdrawal conceptualized as a stressor.Effects of environmental enrichment on ERK1/2 phosphorylation in the rat prefrontal cortex following nicotine-induced sensitization or nicotine self-administrationAssociation of novelty-related behaviors and intravenous cocaine self-administration in Diversity Outbred mice.Nature and nurture: environmental influences on a genetic rat model of depression.Psychological stress, cocaine and natural reward each induce endoplasmic reticulum stress genes in rat brainEnvironmental enrichment alters nicotine-mediated locomotor sensitization and phosphorylation of DARPP-32 and CREB in rat prefrontal cortexInfluence of daily social stimulation on behavioral and physiological outcomes in an animal model of PTSD.Individual differences and social influences on the neurobehavioral pharmacology of abused drugs.Have studies of the developmental regulation of behavioral phenotypes revealed the mechanisms of gene-environment interactions?Enriched environment treatment reverses depression-like behavior and restores reduced hippocampal neurogenesis and protein levels of brain-derived neurotrophic factor in mice lacking its expression through promoter IV.Loss of environmental enrichment increases vulnerability to cocaine addiction.The effects of prenatal cocaine, post-weaning housing and sex on conditioned place preference in adolescent ratsCREB activity in dopamine D1 receptor expressing neurons regulates cocaine-induced behavioral effectsEnvironmental enrichment reduces methamphetamine cue-induced reinstatement but does not alter methamphetamine reward or VMAT2 function.Environmental enrichment alters protein expression as well as the proteomic response to cocaine in rat nucleus accumbens.Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichmentA role for repressive histone methylation in cocaine-induced vulnerability to stress.The interactive effects of environmental enrichment and extinction interventions in attenuating cue-elicited cocaine-seeking behavior in ratsEnvironmental living conditions introduced during forced abstinence alter cocaine-seeking behavior and Fos protein expressionEnvironmental enrichment and gut inflammation modify stress-induced c-Fos expression in the mouse corticolimbic systemGenesis of anxiety, depression, and ongoing abdominal discomfort in ulcerative colitis-like colon inflammation.Activation of CREB in the nucleus accumbens shell produces anhedonia and resistance to extinction of fear in rats.Dynamic proteomics of nucleus accumbens in response to acute psychological stress in environmentally enriched and isolated ratsInoculation stress hypothesis of environmental enrichment.Differential phosphoproteome regulation of nucleus accumbens in environmentally enriched and isolated rats in response to acute stress.Pharmacological manipulation of glucocorticoid receptors differentially affects cocaine self-administration in environmentally enriched and isolated rats.Neuroplasticity underlying the comorbidity of pain and depressionEffect of environmental enrichment on escalation of cocaine self-administration in rats.Environmental enrichment counters cocaine abstinence-induced stress and brain reactivity to cocaine cues but fails to prevent the incubation effectOverexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats.High impulsivity in rats predicts amphetamine conditioned place preferenceCREB1 Genotype Modulates Adaptive Reward-Based Decisions in Humans.Differential Rearing Alters Forced Swim Test Behavior, Fluoxetine Efficacy, and Post-Test Weight Gain in Male RatsAmphetamine self-administration and dopamine function: assessment of gene × environment interactions in Lewis and Fischer 344 rats.The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.Effects of cocaine combined with a social cue on conditioned place preference and nucleus accumbens monoamines after isolation rearing in rats.Prefrontal microRNA-221 Mediates Environmental Enrichment-Induced Increase of Locomotor Sensitivity to Nicotine
P2860
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P2860
Environmental enrichment produces a behavioral phenotype mediated by low cyclic adenosine monophosphate response element binding (CREB) activity in the nucleus accumbens.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Environmental enrichment produ ...... vity in the nucleus accumbens.
@ast
Environmental enrichment produ ...... vity in the nucleus accumbens.
@en
type
label
Environmental enrichment produ ...... vity in the nucleus accumbens.
@ast
Environmental enrichment produ ...... vity in the nucleus accumbens.
@en
prefLabel
Environmental enrichment produ ...... vity in the nucleus accumbens.
@ast
Environmental enrichment produ ...... vity in the nucleus accumbens.
@en
P2093
P2860
P50
P1476
Environmental enrichment produ ...... ivity in the nucleus accumbens
@en
P2093
Ami R Graham
C Nathaniel Roybal
Catharine A Winstanley
Danielle L Graham
David E H Theobald
Eric J Nestler
Ernest F Terwilliger
Imran N Alibhai
Michael T Bardo
Shari G Birnbaum
P2860
P356
10.1016/J.BIOPSYCH.2009.06.022
P407
P577
2010-01-01T00:00:00Z