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Advances in endophenotyping schizophrenia

Advances in endophenotyping schizophrenia

http://www.wikidata.org/entity/Q30494518

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Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis From Linkage Studies to Epigenetics: What We Know and What We Need to Know in the Neurobiology of Schizophrenia Consortium on the Genetics of Schizophrenia (COGS) assessment of endophenotypes for schizophrenia: an introduction to this Special Issue of Schizophrenia Research.Impact of ketamine on neuronal network dynamics: translational modeling of schizophrenia-relevant deficits.Genome-wide scans of genetic variants for psychophysiological endophenotypes: a methodological overview.Removing obstacles in neuroscience drug discovery: the future path for animal models.Heritability and molecular genetic basis of antisaccade eye tracking error rate: a genome-wide association study.Mutual independence of 5-HT(2) and α1 noradrenergic receptors in mediating deficits in sensorimotor gating.Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia.Fine mapping of QTL for prepulse inhibition in LG/J and SM/J mice using F(2) and advanced intercross lines Cross-diagnostic comparison of duration mismatch negativity and P3a in bipolar disorder and schizophrenia.Enduring sensorimotor gating abnormalities following predator exposure or corticotropin-releasing factor in rats: a model for PTSD-like information-processing deficits?Fos expression following regimens of predator stress versus footshock that differentially affect prepulse inhibition in rats Pharmacological stimulation of locus coeruleus reveals a new antipsychotic-responsive pathway for deficient sensorimotor gating.Discrete forebrain neuronal networks supporting noradrenergic regulation of sensorimotor gating.Electroencephalography (EEG) and event-related potentials (ERPs) with human participants Ventral striatal noradrenergic mechanisms contribute to sensorimotor gating deficits induced by amphetamine.Neurophyisological and neurocognitive endophenotypes for schizophrenia genetics research.Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS study.Transcranial magnetic stimulation: a neuroscientific probe of cortical function in schizophrenia.Strategies for the study of neuropsychiatric disorders using endophenotypes in developing countries: a potential databank from china.Functional genetic variants in the vesicular monoamine transporter 1 modulate emotion processing Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia Inhibition of the cortex using transcranial magnetic stimulation in psychiatric populations: current and future directions.A new role for endophenotypes in the GWAS era: functional characterization of risk variants.Social approach in genetically engineered mouse lines relevant to autism Recent progress in the synthesis and characterization of group II metabotropic glutamate receptor allosteric modulators.The clinical staging and the endophenotype approach as an integrative future perspective for psychiatry.P300 and neuropsychological measurements in patients with schizophrenia and their healthy biological siblings Reliability of long-interval cortical inhibition in healthy human subjects: a TMS-EEG study.Independence of familial transmission of mania and depression: results of the NIMH family study of affective spectrum disorders.Cognitive deficits and ethnicity: a cohort study of early psychosis patients in The Netherlands.Gender and estrous cycle influences on behavioral and neurochemical alterations in adult rats neonatally administered ketamine.Evidence for gamma inhibition deficits in the dorsolateral prefrontal cortex of patients with schizophrenia.Core dysfunction in schizophrenia: electrophysiology trait biomarkers.Neuropsychological impairments predict the clinical course in schizophrenia

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Advances in endophenotyping schizophrenia

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World Psychiatry

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Advances in endophenotyping schizophrenia

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David L Braff

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Gregory A Light

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Investigators of the Consortium on the Genetics of Schizophrenia

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Neal R Swerdlow

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Nicholas J Schork

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Tiffany A Greenwood

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P2860

Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia

Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease.

Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia

Modulation of the startle response and startle laterality in relatives of schizophrenic patients and in subjects with schizotypal personality disorder: evidence of inhibitory deficits

The endophenotype concept in psychiatry: etymology and strategic intentions

Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges

Molecular genetic studies of schizophrenia

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