RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects. - Wikidata - wikimedia - TriplyDB

RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects.

RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects.

http://www.wikidata.org/entity/Q30495060

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μ-Opioid receptors and regulators of G protein signaling (RGS) proteins: from a symposium on new concepts in mu-opioid pharmacology Transcriptional regulation of the 5-HT1A receptor: implications for mental illness Conditional disruption of interactions between Gαi2 and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.Reversible inhibitors of regulators of G-protein signaling identified in a high-throughput cell-based calcium signaling assay.Gα(i2)-mediated protection from ischaemic injury is modulated by endogenous RGS proteins in the mouse heart Transcriptional dysregulation of 5-HT1A autoreceptors in mental illness.An essential role for RGS protein/Gαi2 interactions in B lymphocyte-directed cell migration and trafficking Identification of a novel selective serotonin reuptake inhibitor by coupling monoamine transporter-based virtual screening and rational molecular hybridization Regulators of G protein signaling (RGS) proteins as drug targets: modulating G-protein-coupled receptor (GPCR) signal transduction Transcriptional dys-regulation in anxiety and major depression: 5-HT1A gene promoter architecture as a therapeutic opportunity.Roles for Regulator of G Protein Signaling Proteins in Synaptic Signaling and Plasticity.Rethinking 5-HT1A receptors: emerging modes of inhibitory feedback of relevance to emotion-related behavior Modulation of μ-opioid receptor signaling by RGS19 in SH-SY5Y cells.Biphasic Effects of α-Asarone on Immobility in the Tail Suspension Test: Evidence for the Involvement of the Noradrenergic and Serotonergic Systems in Its Antidepressant-Like Activity RGS6 as a Novel Therapeutic Target in CNS Diseases and Cancer.Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis.Influence of RGS2 on sertraline treatment for social anxiety disorder.Control of striatal signaling by g protein regulators.Glycogen Synthase Kinase-3 is an Intermediate Modulator of Serotonin Neurotransmission Genome-wide expression profiling of human lymphoblastoid cell lines identifies CHL1 as a putative SSRI antidepressant response biomarker.Normal Thymocyte Egress, T Cell Trafficking, and CD4+ T Cell Homeostasis Require Interactions between RGS Proteins and Gαi2.Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins Regulator of G protein signaling 4 inhibits human melanoma cells proliferation and invasion through the PI3K/AKT signaling pathway.Evaluation of the Selectivity and Cysteine Dependence of Inhibitors across the Regulator of G Protein-Signaling Family.Zinc Is Involved in Depression by Modulating G Protein-Coupled Receptor Heterodimerization.RGS proteins maintain robustness of GPCR-GIRK coupling by selective stimulation of the G protein subunit Gαo.

P2860

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P2860

RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects.

http://www.wikidata.org/entity/Q30495060

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

RGS inhibition at G(alpha)i2 s ...... diated antidepressant effects.

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RGS inhibition at G(alpha)i2 s ...... diated antidepressant effects.

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type

label

RGS inhibition at G(alpha)i2 s ...... diated antidepressant effects.

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RGS inhibition at G(alpha)i2 s ...... diated antidepressant effects.

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prefLabel

RGS inhibition at G(alpha)i2 s ...... diated antidepressant effects.

@ast

RGS inhibition at G(alpha)i2 s ...... diated antidepressant effects.

@en

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PNAS.1000003107

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Proceedings of the National Academy of Sciences of the United States of America

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RGS inhibition at G(alpha)i2 s ...... ediated antidepressant effects

@en

P2093

Crystal F Clemans

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Emily M Jutkiewicz

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Jeffery N Talbot

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John R Traynor

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Richard M Mortensen

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Steven M Graves

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Xinyan Huang

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P2860

Essential role for RGS9 in opiate action

Multiplicity of mechanisms of serotonin receptor signal transduction

Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay

Targeted inactivation of Galpha(i) does not alter cardiac function or beta-adrenergic sensitivity

Cellular regulation of RGS proteins: modulators and integrators of G protein signaling

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

Differential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Galpha subtype dependent.

Regulator of G protein signaling proteins: novel multifunctional drug targets.

In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice.

The therapeutic role of 5-HT1A and 5-HT2A receptors in depression.

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11086-11091

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10.1073/PNAS.1000003107

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24

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107

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Melanie R Nicol

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2010-06-02T00:00:00Z

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44660126

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20534514

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2890727

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