Regulator of G protein signaling proteins: novel multifunctional drug targets.
about
RGS3 interacts with 14-3-3 via the N-terminal region distinct from the RGS (regulator of G-protein signalling) domainDifferential modulation of mu- and delta-opioid receptor agonists by endogenous RGS4 protein in SH-SY5Y cellsA comprehensive pathway map of epidermal growth factor receptor signalingCrystallization and preliminary X-ray crystallographic analysis of human RGS10 complexed with Galphai3μ-Opioid receptors and regulators of G protein signaling (RGS) proteins: from a symposium on new concepts in mu-opioid pharmacologyPDZ Domain Recognition: Insight from Human Tax-Interacting Protein 1 (TIP-1) Interaction with Target ProteinsRegulators of G-protein signaling in the heart and their potential as therapeutic targets.Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptorsAllosteric inhibition of the regulator of G protein signaling-Galpha protein-protein interaction by CCG-4986RGS9-2 modulates D2 dopamine receptor-mediated Ca2+ channel inhibition in rat striatal cholinergic interneuronsThe evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21.RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects.RINGdb: an integrated database for G protein-coupled receptors and regulators of G protein signaling.Novel peptide ligands of RGS4 from a focused one-bead, one-compound library.Polyplexed flow cytometry protein interaction assay: a novel high-throughput screening paradigm for RGS protein inhibitorsDevelopment of a novel high-throughput screen and identification of small-molecule inhibitors of the Gα-RGS17 protein-protein interaction using AlphaScreen.Variations in Gnai2 and Rgs1 expression affect chemokine receptor signaling and the organization of secondary lymphoid organs.Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteinsSpecificity and promiscuity in human glutaminase interacting protein recognition: insight from the binding of the internal and C-terminal motif.Thinking outside of the "RGS box": new approaches to therapeutic targeting of regulators of G protein signaling.Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice.SST2, a regulator of G-protein signaling for the Candida albicans mating response pathway.Characterization of the GRK2 binding site of Galphaq.A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteinsConformational dynamics of a regulator of G-protein signaling protein reveals a mechanism of allosteric inhibition by a small molecule.Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 alleleRegulator of G protein signaling 2 (RGS2) and RGS4 form distinct G protein-dependent complexes with protease activated-receptor 1 (PAR1) in live cells.Identifying functional gene regulatory network phenotypes underlying single cell transcriptional variability.Regulators of G protein signaling (RGS) proteins as drug targets: modulating G-protein-coupled receptor (GPCR) signal transductionGαi2 signaling: friend or foe in cardiac injury and heart failure?Recent advances in drug action and therapeutics: relevance of novel concepts in G-protein-coupled receptor and signal transduction pharmacology.Phospholipase Cepsilon is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferationCardiotonic steroids stabilize regulator of G protein signaling 2 protein levelsActivation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis.RGS Proteins and Gαi2 Modulate Sleep, Wakefulness, and Disruption of Sleep/ Wake States after Isoflurane and Sevoflurane Anesthesia.The downstream regulation of chemokine receptor signalling: implications for atherosclerosisMicrofabricated channel array electrophoresis for characterization and screening of enzymes using RGS-G protein interactions as a model system.Regulation of the trafficking and function of G protein-coupled receptors by Rab1 GTPase in cardiomyocytes.Regulator of G protein signaling protein suppression of Galphao protein-mediated alpha2A adrenergic receptor inhibition of mouse hippocampal CA3 epileptiform activityG protein betagamma subunits as targets for small molecule therapeutic development.
P2860
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P2860
Regulator of G protein signaling proteins: novel multifunctional drug targets.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Regulator of G protein signaling proteins: novel multifunctional drug targets.
@ast
Regulator of G protein signaling proteins: novel multifunctional drug targets.
@en
Regulator of G protein signaling proteins: novel multifunctional drug targets.
@nl
type
label
Regulator of G protein signaling proteins: novel multifunctional drug targets.
@ast
Regulator of G protein signaling proteins: novel multifunctional drug targets.
@en
Regulator of G protein signaling proteins: novel multifunctional drug targets.
@nl
prefLabel
Regulator of G protein signaling proteins: novel multifunctional drug targets.
@ast
Regulator of G protein signaling proteins: novel multifunctional drug targets.
@en
Regulator of G protein signaling proteins: novel multifunctional drug targets.
@nl
P1476
Regulator of G protein signaling proteins: novel multifunctional drug targets.
@en
P2093
P304
P407
P577
2001-06-01T00:00:00Z