The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis
about
Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2Role of Nrf2 in oxidative stress and toxicityDimethyl fumarate for multiple sclerosisDimethyl fumarate for multiple sclerosisMucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel DiseaseRedox regulation of T-cell function: from molecular mechanisms to significance in human health and diseaseBinding mode and structure-activity relationships around direct inhibitors of the Nrf2-Keap1 complexGenetic ablation of Nrf2/antioxidant response pathway in Alexander disease mice reduces hippocampal gliosis but does not impact survivalThe Nrf2 activator tBHQ inhibits T cell activation of primary human CD4 T cellsRegulation of APC development, immune response, and autoimmunity by Bach1/HO-1 pathway in miceThe Nrf2 activator, tBHQ, differentially affects early events following stimulation of Jurkat cellsNrf2 regulates chronic lung inflammation and B-cell responses to nontypeable Haemophilus influenzaeNrf2-dysregulation correlates with reduced synthesis and low glutathione levels in experimental autoimmune encephalomyelitisMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseTriterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitisNrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcriptionTh2 skewing by activation of Nrf2 in CD4(+) T cellsEmerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection12/15-Lipoxygenase-mediated enzymatic lipid oxidation regulates DC maturation and function.Deficits in bioenergetics and impaired immune response in granulocytes from children with autismFumarate treatment in progressive forms of multiple sclerosis: first results of a single-center observational studyRedox-based therapeutics in neurodegenerative disease.Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.Increased Alzheimer's disease-like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagyCannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice.Cell type-specific Nrf2 expression in multiple sclerosis lesions.Changes in 20S subunit composition are largely responsible for altered proteasomal activities in experimental autoimmune encephalomyelitis.Whole-Body In Vivo Monitoring of Inflammatory Diseases Exploiting Human Interleukin 6-Luciferase Transgenic Mice.Ginger-derived nanoparticles protect against alcohol-induced liver damage.Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity.Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model.Nrf2 to pre-condition the brain against injury caused by products of hemolysis after ICH.Nrf2--a therapeutic target for the treatment of neurodegenerative diseases.Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2.Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice.Loss of Nrf2 exacerbates the visual deficits and optic neuritis elicited by experimental autoimmune encephalomyelitis.Nrf2-ARE stress response mechanism: a control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases.The molecular basis of neurodegeneration in multiple sclerosis.The fumaric acid ester BG-12: a new option in MS therapy.Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases.
P2860
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P2860
The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The absence of the pro-antioxi ...... l autoimmune encephalomyelitis
@ast
The absence of the pro-antioxi ...... l autoimmune encephalomyelitis
@en
type
label
The absence of the pro-antioxi ...... l autoimmune encephalomyelitis
@ast
The absence of the pro-antioxi ...... l autoimmune encephalomyelitis
@en
prefLabel
The absence of the pro-antioxi ...... l autoimmune encephalomyelitis
@ast
The absence of the pro-antioxi ...... l autoimmune encephalomyelitis
@en
P2093
P2860
P356
P1476
The absence of the pro-antioxi ...... l autoimmune encephalomyelitis
@en
P2093
Charlotte Ward
Delinda A Johnson
Jeffrey A Johnson
Sara Amirahmadi
Zsuszanna Fabry
P2860
P304
P356
10.1093/TOXSCI/KFP274
P577
2009-11-12T00:00:00Z