Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. - Wikidata - wikimedia - TriplyDB

Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits.

Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits.

http://www.wikidata.org/entity/Q30497694

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Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease Phospholipase D as a therapeutic target in brain disorders Mammalian phospholipase D physiological and pathological roles Functional regulation of phospholipase D expression in cancer and inflammation Golgi membrane dynamics and lipid metabolism Dopamine-induced plasticity, phospholipase D (PLD) activity and cocaine-cue behavior depend on PLD-linked metabotropic glutamate receptors in amygdala The impact of chronic stress on the rat brain lipidome The phospholipase D superfamily as therapeutic targets Phospholipases D1 and D2 Suppress Appetite and Protect against Overweight Using neurolipidomics to identify phospholipid mediators of synaptic (dys)function in Alzheimer's Disease.Modeling resilience to schizophrenia in genetically modified mice: a novel approach to drug discovery.Kinetic disruption of lipid rafts is a mechanosensor for phospholipase D Brain lipidomes of subcortical ischemic vascular dementia and mixed dementia Lipocalin 2 modulates the cellular response to amyloid beta.Phospholipase D facilitates efficient entry of influenza virus, allowing escape from innate immune inhibition Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates Alzheimer's disease risk genes and mechanisms of disease pathogenesis Deficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment.PLD3 is accumulated on neuritic plaques in Alzheimer's disease brains.COPI acts in both vesicular and tubular transport.The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease.Phospholipase D: enzymology, functionality, and chemical modulation Comparative lipidomic analysis of mouse and human brain with Alzheimer disease.Lipids under stress--a lipidomic approach for the study of mood disorders.Linking lipids to Alzheimer's disease: cholesterol and beyond.The phospholipase D1 pathway modulates macroautophagy Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells.Lipidomics: when apocrypha becomes canonical.The Phospholipase D2 Knock Out Mouse Has Ectopic Purkinje Cells and Suffers from Early Adult-Onset Anosmia.Chronic nicotine differentially affects murine transcriptome profiling in isolated cortical interneurons and pyramidal neurons.Physiological and pathophysiological roles for phospholipase D.Diacylglycerol, phosphatidic acid, and their metabolic enzymes in synaptic vesicle recycling.Modulation of 5-lipoxygenase in proteotoxicity and Alzheimer's disease.Reduction of synaptojanin 1 ameliorates synaptic and behavioral impairments in a mouse model of Alzheimer's disease.Key roles for the lipid signaling enzyme phospholipase d1 in the tumor microenvironment during tumor angiogenesis and metastasis.Phospholipase D2 mediates survival signaling through direct regulation of Akt in glioblastoma cells.Effect of xiaoyaosan decoction on learning and memory deficit in rats induced by chronic immobilization stress.Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system.Temporal production of the signaling lipid phosphatidic acid by phospholipase D2 determines the output of extracellular signal-regulated kinase signaling in cancer cells

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P2860

Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits.

http://www.wikidata.org/entity/Q30497694

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Phospholipase d2 ablation amel ...... nction and cognitive deficits.

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Phospholipase d2 ablation amel ...... nction and cognitive deficits.

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type

label

Phospholipase d2 ablation amel ...... nction and cognitive deficits.

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Phospholipase d2 ablation amel ...... nction and cognitive deficits.

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prefLabel

Phospholipase d2 ablation amel ...... nction and cognitive deficits.

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Phospholipase d2 ablation amel ...... nction and cognitive deficits.

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JNEUROSCI.3317-10.2010

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Journal of Neuroscience

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Phospholipase d2 ablation amel ...... nction and cognitive deficits.

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Agnieszka Staniszewski

http://www.w3.org/2001/XMLSchema#string

Gilbert Di Paolo

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Guanghou Shui

http://www.w3.org/2001/XMLSchema#string

Hong Zhang

http://www.w3.org/2001/XMLSchema#string

Huasong Tian

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Karen E Duff

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Lili Wang

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Markus R Wenk

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Mikael Laredo

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Robin B Chan

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P2860

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis

Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.

Emotion circuits in the brain

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast.

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

Phospholipase D: a lipid centric review

Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

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16419-16428

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scholarly article

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10.1523/JNEUROSCI.3317-10.2010

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49

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30

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Tiago Gil Oliveira

Ottavio Arancio

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2010-12-01T00:00:00Z

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49673869

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21147981

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Alzheimer's disease

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3004537

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