Age-related alterations in the dynamic behavior of microglia. - Wikidata - wikimedia - TriplyDB

Age-related alterations in the dynamic behavior of microglia.

Age-related alterations in the dynamic behavior of microglia.

http://www.wikidata.org/entity/Q30498664

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Targeting innate immunity for neurodegenerative disorders of the central nervous system Microglial cell dysregulation in brain aging and neurodegeneration From the Cajal alumni Achúcarro and Río-Hortega to the rediscovery of never-resting microglia The role of free radicals in the aging brain and Parkinson's Disease: convergence and parallelism Receptors, ion channels, and signaling mechanisms underlying microglial dynamics Contribution of microglia-mediated neuroinflammation to retinal degenerative diseases Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase.Microglia communication: Parallels between aging and Alzheimer's disease Adaptive Müller cell responses to microglial activation mediate neuroprotection and coordinate inflammation in the retina Microglial Function across the Spectrum of Age and Gender Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling.Microglia as a critical player in both developmental and late-life CNS pathologies.Effects of aging and sensory loss on glial cells in mouse visual and auditory cortices.In vivo dynamics of innate immune sentinels in the CNS.Microglia processes associate with diffusely injured axons following mild traumatic brain injury in the micro pig.Proteomic anaysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response.Microglia change from a reactive to an age-like phenotype with the time in culture Aging reduces glial uptake and promotes extracellular accumulation of Aβ from a lentiviral vector.Retinal dendritic cell recruitment, but not function, was inhibited in MyD88 and TRIF deficient mice.Prospective study of common variants in CX3CR1 and risk of macular degeneration: pooled analysis from 5 long-term studies.SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.Homeostatic and injury-induced microglia behavior in the aging brain.Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease Microglia in action: how aging and injury can change the brain's guardians.Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity.7-Ketocholesterol increases retinal microglial migration, activation, and angiogenicity: a potential pathogenic mechanism underlying age-related macular degeneration Immune aging, dysmetabolism, and inflammation in neurological diseases.Retinal phagocytes in age-related macular degeneration Microglia in the developing brain: a potential target with lifetime effects.Nucleotides released from Aβ₁₋₄₂ -treated microglial cells increase cell migration and Aβ₁₋₄₂ uptake through P2Y₂ receptor activation Interferon-beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization.Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration Expression pattern of Ccr2 and Cx3cr1 in inherited retinal degeneration Targeting translocator protein (18 kDa) (TSPO) dampens pro-inflammatory microglia reactivity in the retina and protects from degeneration.Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration Characteristics of spinal microglia in aged and obese mice: potential contributions to impaired sensory behavior A2E accumulation influences retinal microglial activation and complement regulation Microglia in the TBI brain: The good, the bad, and the dysregulated.Aging Changes in Retinal Microglia and their Relevance to Age-related Retinal Disease.

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P2860

Age-related alterations in the dynamic behavior of microglia.

http://www.wikidata.org/entity/Q30498664

description

2010 nî lūn-bûn

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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

Age-related alterations in the dynamic behavior of microglia.

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Age-related alterations in the dynamic behavior of microglia.

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type

label

Age-related alterations in the dynamic behavior of microglia.

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Age-related alterations in the dynamic behavior of microglia.

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prefLabel

Age-related alterations in the dynamic behavior of microglia.

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Age-related alterations in the dynamic behavior of microglia.

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J.1474-9726.2010.00660.X

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Age-related alterations in the dynamic behavior of microglia.

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Aurora M Fontainhas

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Juan Amaral

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Mausam R Damani

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Robert N Fariss

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P2860

Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes

New insights into neuron-glia communication

Exploring the full spectrum of macrophage activation

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

Receptors for purines and pyrimidines

P2Y12 receptor-mediated integrin-beta1 activation regulates microglial process extension induced by ATP

The P2Y12 receptor regulates microglial activation by extracellular nucleotides

ATP mediates rapid microglial response to local brain injury in vivo

Origin and physiological roles of inflammation

Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

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