Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function
about
Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model.Quantitative analysis of 5HT(2C) receptor RNA editing patterns in psychiatric disordersSerotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorderEndocytosis promotes rapid dopaminergic signalingAβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic lossBlinded prospective evaluation of computer-based mechanistic schizophrenia disease model for predicting drug responseMice Lacking Serotonin 2C Receptors Have increased Affective Responses to Aversive Stimuli.5-hydroxytryptamine 2C receptors in the dorsal striatum mediate stress-induced interference with negatively reinforced instrumental escape behavior.Impact of serotonin (5-HT)2C receptors on executive control processes.Editing of neurotransmitter receptor and ion channel RNAs in the nervous systemA computer-based quantitative systems pharmacology model of negative symptoms in schizophrenia: exploring glycine modulation of excitation-inhibition balance.The serotonin 5-HT2C receptor and the non-addictive nature of classic hallucinogens.Dissociable effects of 5-HT2C receptor antagonism and genetic inactivation on perseverance and learned non-reward in an egocentric spatial reversal task.Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophreniaEndocannabinoid-dopamine interactions in striatal synaptic plasticity.Striatal dopamine release and genetic variation of the serotonin 2C receptor in humansLearning From Animal Models of Obsessive-Compulsive Disorder5-HT(2A) receptor blockade and 5-HT(2C) receptor activation interact to reduce cocaine hyperlocomotion and Fos protein expression in the caudate-putamenDispensable, redundant, complementary, and cooperative roles of dopamine, octopamine, and serotonin in Drosophila melanogaster.Striatal serotonin 2C receptors decrease nigrostriatal dopamine release by increasing GABA-A receptor tone in the substantia nigra.A novel aminotetralin-type serotonin (5-HT) 2C receptor-specific agonist and 5-HT2A competitive antagonist/5-HT2B inverse agonist with preclinical efficacy for psychoses.Multiple controls exerted by 5-HT2C receptors upon basal ganglia function: from physiology to pathophysiology.Serotoninergic and dopaminergic modulation of cortico-striatal circuit in executive and attention deficits induced by NMDA receptor hypofunction in the 5-choice serial reaction time task.Prediction of Efficacy of Vabicaserin, a 5-HT2C Agonist, for the Treatment of Schizophrenia Using a Quantitative Systems Pharmacology Model.A heuristic model for working memory deficit in schizophreniaStimulation of medial prefrontal cortex serotonin 2C (5-HT(2C)) receptors attenuates cocaine-seeking behavior.Impulsive action in the 5-choice serial reaction time test in 5-HT₂c receptor null mutant mice.5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice.Reduced activity at the 5-HT(2C) receptor enhances reversal learning by decreasing the influence of previously non-rewarded associations.Tph2 gene deletion enhances amphetamine-induced hypermotility: effect of 5-HT restoration and role of striatal noradrenaline release.Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice.
P2860
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P2860
Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Impact of serotonin 2C recepto ...... atal dopamine pathway function
@ast
Impact of serotonin 2C recepto ...... atal dopamine pathway function
@en
type
label
Impact of serotonin 2C recepto ...... atal dopamine pathway function
@ast
Impact of serotonin 2C recepto ...... atal dopamine pathway function
@en
prefLabel
Impact of serotonin 2C recepto ...... atal dopamine pathway function
@ast
Impact of serotonin 2C recepto ...... atal dopamine pathway function
@en
P2093
P2860
P1476
Impact of serotonin 2C recepto ...... atal dopamine pathway function
@en
P2093
Antonello Bonci
Ennio Esposito
F Woodward Hopf
Laura O'Dell
Laurence H Tecott
Loren H Parsons
Luna Abdallah
Marco Giorgetti
Massimo Pierucci
Minke Jongsma
P2860
P304
P356
10.1523/JNEUROSCI.3905-08.2009
P407
P577
2009-06-01T00:00:00Z