about
A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoniA tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers.REAPR: a universal tool for genome assembly evaluationGenomic insights into the origin of parasitism in the emerging plant pathogen Bursaphelenchus xylophilusAssemblathon 2: evaluating de novo methods of genome assembly in three vertebrate speciesAtypical mitogen-activated protein kinase phosphatase implicated in regulating transition from pre-S-Phase asexual intraerythrocytic development of Plasmodium falciparumWhole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplificationKinetoplastid Phylogenomics Reveals the Evolutionary Innovations Associated with the Origins of ParasitismA comprehensive evaluation of rodent malaria parasite genomes and gene expressionLong- and short-term selective forces on malaria parasite genomesPlasmodium malariae and P. ovale genomes provide insights into malaria parasite evolutionA new Plasmodium vivax reference sequence with improved assembly of the subtelomeres reveals an abundance of pir genesIVA: accurate de novo assembly of RNA virus genomesPyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum.BamView: visualizing and interpretation of next-generation sequencing read alignmentsProteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteinsA novel multiple-stage antimalarial agent that inhibits protein synthesisComparative genomics in Chlamydomonas and Plasmodium identifies an ancient nuclear envelope protein family essential for sexual reproduction in protists, fungi, plants, and vertebrates.Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous VacuoleGenome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts.An In-Solution Hybridisation Method for the Isolation of Pathogen DNA from Human DNA-rich Clinical Samples for Analysis by NGSAntigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species.Efficient depletion of host DNA contamination in malaria clinical sequencing.Optimizing Illumina next-generation sequencing library preparation for extremely AT-biased genomes.The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interactionReRep: computational detection of repetitive sequences in genome survey sequences (GSS).AnEnPi: identification and annotation of analogous enzymes.BamView: viewing mapped read alignment data in the context of the reference sequenceExtreme mutation bias and high AT content in Plasmodium falciparum.Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites.Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies.New insights into the blood-stage transcriptome of Plasmodium falciparum using RNA-Seq.Targeted disruption of py235ebp-1: invasion of erythrocytes by Plasmodium yoelii using an alternative Py235 erythrocyte binding protein.A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.A scalable pipeline for highly effective genetic modification of a malaria parasite.Two nonrecombining sympatric forms of the human malaria parasite Plasmodium ovale occur globally.Characterization and gene expression analysis of the cir multi-gene family of Plasmodium chabaudi chabaudi (AS).Divergent mitochondrial respiratory chains in phototrophic relatives of apicomplexan parasites.Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites.Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas' disease treatment.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Thomas D Otto
@en
Thomas D Otto
@es
Thomas D Otto
@nl
Thomas D Otto
@sl
Thomas Otto
@fr
type
label
Thomas D Otto
@en
Thomas D Otto
@es
Thomas D Otto
@nl
Thomas D Otto
@sl
Thomas Otto
@fr
prefLabel
Thomas D Otto
@en
Thomas D Otto
@es
Thomas D Otto
@nl
Thomas D Otto
@sl
Thomas Otto
@fr
P106
P21
P2456
P31
P496
0000-0002-1246-7404