The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation. - Wikidata - wikimedia - TriplyDB

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.

http://www.wikidata.org/entity/Q30503467

about

Pluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical application Detachment of surface membrane invagination systems by cationic amphiphilic drugs Megakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiation Gaucher disease: transcriptome analyses using microarray or mRNA sequencing in a Gba1 mutant mouse model treated with velaglucerase alfa or imiglucerase Does size matter in platelet production?Inherited thrombocytopenias: an approach to diagnosis and management.Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation.Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation.Protein kinase A activation by the anti-cancer drugs ABT-737 and thymoquinone is caspase-3-dependent and correlates with platelet inhibition and apoptosis.The incredible journey: From megakaryocyte development to platelet formation.Microtubule and cortical forces determine platelet size during vascular platelet production.Platelets and cancer: a casual or causal relationship: revisited.βII-Spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and Wnt signaling by regulation of Wnt inhibitor kallistatin.Regulation of actin polymerization by tropomodulin-3 controls megakaryocyte actin organization and platelet biogenesis.GPIbα regulates platelet size by controlling the subcellular localization of filamin Feisty filaments: actin dynamics in the red blood cell membrane skeleton.JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia.Proplatelet generation in the mouse requires PKCε-dependent RhoA inhibition.New explanations for old observations: marginal band coiling during platelet activation.Cdc42-dependent F-actin dynamics drive structuration of the demarcation membrane system in megakaryocytes.Membrane grease eases platelet maturation.Balance of microtubule stiffness and cortical tension determines the size of blood cells with marginal band across species.The cell division control protein 42-Src family kinase-neural Wiskott-Aldrich syndrome protein pathway regulates human proplatelet formation.Proteomics Studies on the three Larval Stages of Development and Metamorphosis of Babylonia areolata.

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P2860

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.

http://www.wikidata.org/entity/Q30503467

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

The spectrin-based membrane sk ...... atelet and platelet formation.

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The spectrin-based membrane sk ...... atelet and platelet formation.

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The spectrin-based membrane sk ...... atelet and platelet formation.

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Antonija J Begonja

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Eva C Alden

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Hongbei Wang

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John H Hartwig

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Jonathan N Thon

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Joseph E Italiano

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Nancy J Wandersee

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Sunita Patel-Hett

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P2860

Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues

Properties of human red cell spectrin heterodimer (side-to-side) assembly and identification of an essential nucleation site

Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

Calpain proteolysis of alpha II-spectrin in the normal adult human brain

Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis.

Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome

Thrombosis and secondary hemochromatosis play major roles in the pathogenesis of jaundiced and spherocytic mice, murine models for hereditary spherocytosis

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development.

Properties of the demarcation membrane system in living rat megakaryocytes.

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1641-1652

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10.1182/BLOOD-2011-01-330688

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