Microtubule and cortical forces determine platelet size during vascular platelet production. - Wikidata - wikimedia - TriplyDB

Microtubule and cortical forces determine platelet size during vascular platelet production.

Microtubule and cortical forces determine platelet size during vascular platelet production.

http://www.wikidata.org/entity/Q34278424

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A secreted tyrosine kinase acts in the extracellular environment Linkage between the mechanisms of thrombocytopenia and thrombopoiesis IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs.Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans Motor-driven marginal band coiling promotes cell shape change during platelet activation.Does size matter in platelet production?Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling The abnormal proplatelet formation in MYH9-related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibition.TUBB1 mutation disrupting microtubule assembly impairs proplatelet formation and results in congenital macrothrombocytopenia.Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation.Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein.Cytoskeletal perturbation leads to platelet dysfunction and thrombocytopenia in variant forms of Glanzmann thrombasthenia Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation.Inherited thrombocytopenias-recent advances in clinical and molecular aspects.Evidence for shear-mediated Ca2+ entry through mechanosensitive cation channels in human platelets and a megakaryocytic cell line.The incredible journey: From megakaryocyte development to platelet formation.Platelet bioreactor-on-a-chip.Shear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells.Animating platelet production adds physiological context.Comparative analysis of human ex vivo-generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale.Multistage vector (MSV) therapeutics.Identifying and enriching platelet-producing human stem cell-derived megakaryocytes using factor V uptake.Cell Surface Mechanochemistry and the Determinants of Bleb Formation, Healing, and Travel Velocity.Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4.Proplatelet generation in the mouse requires PKCε-dependent RhoA inhibition.Challenges and promises for the development of donor-independent platelet transfusions.New explanations for old observations: marginal band coiling during platelet activation.Human thrombopoiesis depends on Protein kinase Cδ/protein kinase Cε functional couple.Balance of microtubule stiffness and cortical tension determines the size of blood cells with marginal band across species.Scalable generation of universal platelets from human induced pluripotent stem cells.Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia.Toward the Relevance of Platelet Subpopulations for Transfusion Medicine.Method for the simulation of blood platelet shape and its evolution during activation.Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment.Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia

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P2860

Microtubule and cortical forces determine platelet size during vascular platelet production.

http://www.wikidata.org/entity/Q34278424

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2012 nî lūn-bûn

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2012 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2012 թվականի մայիսին հրատարակված գիտական հոդված

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Microtubule and cortical force ...... vascular platelet production.

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Microtubule and cortical force ...... vascular platelet production.

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Microtubule and cortical force ...... vascular platelet production.

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Microtubule and cortical force ...... vascular platelet production.

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Microtubule and cortical force ...... vascular platelet production.

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Microtubule and cortical force ...... vascular platelet production.

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Microtubule and cortical force ...... vascular platelet production.

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Microtubule and cortical force ...... vascular platelet production.

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Microtubule and cortical force ...... vascular platelet production.

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Microtubule and cortical force ...... vascular platelet production.

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P2093

Antonija Jurak Begonja

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Hannah Macleod

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Jie Zhu

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John H Hartwig

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Jonathan N Thon

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Joseph E Italiano

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Kun-Chun Lee

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P2860

A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function

Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules.

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.

Laser scanning cytometry: principles and applications

Mechanisms and implications of platelet discoid shape.

Qualitative disorders of platelets and megakaryocytes.

The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway.

Dominant inheritance of a novel integrin beta3 mutation associated with a hereditary macrothrombocytopenia and platelet dysfunction in two Italian families.

FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly.

A comparison of platelet size, latelet count, and platelet 35S incorporation as assays for thrombopoietin.

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