Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone. - Wikidata - wikimedia - TriplyDB

Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone.

Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone.

http://www.wikidata.org/entity/Q30504293

about

Orai1 calcium channels in the vasculature Superoxide enhances Ca2+ entry through L-type channels in the renal afferent arteriole.Store-operated calcium entry and diabetic complications Reactive oxygen species in inflammation and tissue injury Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli.Increased glomerular filtration rate and impaired contractile function of mesangial cells in TRPC6 knockout mice.Role of transient receptor potential channel 6 in the odontogenic differentiation of human dental pulp cells.The role of canonical transient receptor potential channels in seizure and excitotoxicity PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity.High glucose induces podocyte apoptosis by stimulating TRPC6 via elevation of reactive oxygen species Uncoupling protein-2 mediates DPP-4 inhibitor-induced restoration of endothelial function in hypertension through reducing oxidative stress.Glutathionylation of the aquaporin-2 water channel: a novel post-translational modification modulated by the oxidative stress Role of TRP channels in the cardiovascular system.Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels Interferon regulatory factor 7 regulates airway epithelial cell responses to human rhinovirus infection.Sodium tanshinone IIA sulfonate inhibits canonical transient receptor potential expression in pulmonary arterial smooth muscle from pulmonary hypertensive rats.The synthetic triterpenoid, RTA 405, increases the glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells Local coupling of TRPC6 to ANO1/TMEM16A channels in smooth muscle cells amplifies vasoconstriction in cerebral arteries.TRPC6 channel activation promotes neonatal glomerular mesangial cell apoptosis via calcineurin/NFAT and FasL/Fas signaling pathways.20-Hydroxyeicosatetraenoic Acid (20-HETE) Modulates Canonical Transient Receptor Potential-6 (TRPC6) Channels in Podocytes Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.ROS-activated calcium signaling mechanisms regulating endothelial barrier function.Canonical Transient Receptor Potential 6 Channel: A New Target of Reactive Oxygen Species in Renal Physiology and Pathology.Renoprotection: focus on TRPV1, TRPV4, TRPC6 and TRPM2.Renal vasoconstriction by vasopressin V1a receptors is modulated by nitric oxide, prostanoids, and superoxide but not the ADP ribosyl cyclase CD38.Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability.Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice.Enhanced Mitochondrial Transient Receptor Potential Channel, Canonical Type 3-Mediated Calcium Handling in the Vasculature From Hypertensive Rats.A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling.Angiotensin II activation of TRPC6 channels in rat podocytes requires generation of reactive oxygen species.New Aspects of the Contribution of ER to SOCE Regulation: TRPC Proteins as a Link Between Plasma Membrane Ion Transport and Intracellular Ca2+ Stores.TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca(2+) concentration in mouse cardiomyocytes.Short Term High Glucose Treatment Decreased Abundance of Orai1 Protein through Posttranslational Mechanisms in Rat Mesangial Cells.TRPC6 and TRPC4 Heteromultimerization Mediates Store Depletion-Activated NCX1 Reversal in Proliferative Vascular Smooth Muscle Cells.

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P2860

Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone.

http://www.wikidata.org/entity/Q30504293

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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Journal of Biological Chemistry

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Reactive oxygen species-mediat ...... ictor-regulated vascular tone.

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Ali Winters

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Irina Akopova

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Jeong Hee Hong

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Lutz Birnbaumer

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Min Ding

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Rong Ma

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Sarabeth Graham

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Shao-Hua Yang

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Shmuel Muallem

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Yanfeng Ding

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P2860

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

Regulation of TRPC6 channel activity by tyrosine phosphorylation

Novel gp91(phox) homologues in vascular smooth muscle cells : nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways

Canonical transient receptor potential 6 (TRPC6), a redox-regulated cation channel

Hydrogen peroxide stimulates c-Src-mediated big mitogen-activated protein kinase 1 (BMK1) and the MEF2C signaling pathway in PC12 cells: potential role in cell survival following oxidative insults

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

NAD(P)H oxidase: role in cardiovascular biology and disease

The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel.

Increased vascular smooth muscle contractility in TRPC6-/- mice.

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10.1074/JBC.M111.248344

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36

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