about
The mating competence of geographically diverse Leishmania major strains in their natural and unnatural sand fly vectorsThe genome of the kinetoplastid parasite, Leishmania majorDemonstration of genetic exchange during cyclical development of Leishmania in the sand fly vectorMigratory dermal dendritic cells act as rapid sensors of protozoan parasitesRetention and loss of RNA interference pathways in trypanosomatid protozoansThe susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposingA Narnavirus-Like Element from the Trypanosomatid Protozoan Parasite Leptomonas seymouriIdentification of a DNA fragment that increases mitotic stability of episomal linear DNAs in Leishmania major.Isolation of genes mediating resistance to inhibitors of nucleoside and ergosterol metabolism in Leishmania by overexpression/selection.REDHORSE-REcombination and Double crossover detection in Haploid Organisms using next-geneRation SEquencing data.The Leishmania GDP-mannose transporter is an autonomous, multi-specific, hexameric complex of LPG2 subunits.Transposon mutagenesis of Mycobacterium marinum identifies a locus linking pigmentation and intracellular survival.Identification of genes encoding arabinosyltransferases (SCA) mediating developmental modifications of lipophosphoglycan required for sand fly transmission of leishmania major.Expression profiling using random genomic DNA microarrays identifies differentially expressed genes associated with three major developmental stages of the protozoan parasite Leishmania major.A novel role for Stat1 in phagosome acidification and natural host resistance to intracellular infection by Leishmania majorDegradation of host sphingomyelin is essential for Leishmania virulence.Leishmania major glycosylation mutants require phosphoglycans (lpg2-) but not lipophosphoglycan (lpg1-) for survival in permissive sand fly vectors.Infection with arginase-deficient Leishmania major reveals a parasite number-dependent and cytokine-independent regulation of host cellular arginase activity and disease pathogenesis.Leishmania major intracellular survival is not altered in SHP-1 deficient mev or CD45-/- mice.Phospholipid and sphingolipid metabolism in Leishmania.Therapeutic efficacy of stable analogues of vasoactive intestinal peptide against pathogens.A lipophosphoglycan-independent development of Leishmania in permissive sand flies.Leishmania major survival in selective Phlebotomus papatasi sand fly vector requires a specific SCG-encoded lipophosphoglycan galactosylation pattern.Genetic metabolic complementation establishes a requirement for GDP-fucose in Leishmania.Development of a safe live Leishmania vaccine line by gene replacement.Eukaryotic UDP-galactopyranose mutase (GLF gene) in microbial and metazoal pathogens.Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite PersistenceMonitoring the efficacy of antimicrobial photodynamic therapy in a murine model of cutaneous leishmaniasis using L. major expressing GFP.Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes.Phosphoproteome dynamics reveal heat-shock protein complexes specific to the Leishmania donovani infectious stage.A role for tetrahydrofolates in the metabolism of iron-sulfur clusters in all domains of life.Proteophosphoglycan confers resistance of Leishmania major to midgut digestive enzymes induced by blood feeding in vector sand flies.Expansion of the target of rapamycin (TOR) kinase family and function in Leishmania shows that TOR3 is required for acidocalcisome biogenesis and animal infectivity.Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania majorBiochemical and genetic analysis of methylenetetrahydrofolate reductase in Leishmania metabolism and virulence.Heterologous expression of Trypanosoma cruzi trans-sialidase in Leishmania major enhances virulenceLeishmania LPG3 encodes a GRP94 homolog required for phosphoglycan synthesis implicated in parasite virulence but not viabilityIdentification of a compensatory mutant (lpg2-REV) of Leishmania major able to survive as amastigotes within macrophages without LPG2-dependent glycoconjugates and its significance to virulence and immunization strategiesSphingolipids in parasitic protozoaImprovements in transfection efficiency and tests of RNA interference (RNAi) approaches in the protozoan parasite Leishmania.
P50
Q21144888-30764892-9A70-431F-B112-DC26C9AF43EDQ22065797-B131F86E-0FE5-4388-807B-D69C70C9723EQ24649510-C25EE11D-DBC9-44F7-BE20-F5C46D166EECQ27318300-05DA9971-C8FC-41BD-9A9B-5617BE615547Q28475957-1D0CD04B-6D6E-4F5C-84CD-258DA051275DQ28476644-7B2BACFF-3DDF-4111-A536-FD2DBB419884Q28831312-8A0C04CB-5368-4CBE-8275-84C83E7F3042Q30790742-4970B4D4-3477-434C-BCB0-02A67A6AA03EQ30828671-AFCF158D-8E60-4B92-A5ED-662E15EB2560Q30909563-61884E60-64A3-4DBF-90ED-085CA87CBD62Q33179802-C8BF91ED-300A-48AF-B1E3-C6BF771D34C3Q33185787-680E9CCB-77D9-4C6F-8708-620B1B3485F3Q33187035-2D1617C4-053D-48E7-B5E6-A3873191F916Q33202821-BDF2DA9C-3DEB-4C35-B42C-C2C5A49B5DFCQ33432700-CF3D7B98-9F65-4A5A-BED4-117BC0CBC149Q33518485-22E5B53F-1A5E-4FAF-80F2-542D78875231Q33525007-B568EC27-0198-4ABB-9817-08118FA35361Q33566856-F8821568-4867-41F9-A80C-6441CBDBDDC1Q33610552-F494D1E3-E1B1-4495-B006-1AC4A91640CCQ33625755-63D4FE06-4CEF-493F-8884-8980543AF5D6Q33652057-C4E48663-0652-4806-91F5-6227F5517E60Q33732048-8FEC5B8A-B64A-43EF-A664-0B6BBED83684Q33750020-D6737FFF-376F-4744-A85E-2689C1D4F737Q33826510-9DAE23A0-2749-49BB-9DCB-A2E82E83DDC0Q33830649-A5D4FDC1-E717-4657-95CF-A92825D90DA8Q33856548-1A5DF070-B984-4F1E-B9E5-CEA9AACA332EQ33858945-08DA91EE-5C3B-434F-93E6-AF35F67049A8Q33876004-3712307B-4157-4907-8E97-AAB5ED07B91EQ33925389-B361899F-848F-4811-8937-0FE74FB3EE32Q33929494-36C1AD61-4050-44BE-9969-D3050B05223CQ33934805-C696276A-54EC-416C-A2A2-5AC630046913Q33938758-B2B2BA7B-5B9F-40D4-9888-7EE686AAA79BQ33977840-7F3DB925-1B4A-410E-937D-BACB41FCF996Q33979086-18AB7B6E-1F36-48D0-A743-CDCD8E781AE0Q34000109-9063E01B-9D26-4CE8-9635-370FC91924AFQ34004312-B75C9F3A-8B1A-4646-9FD6-6EA42BF38139Q34090960-5EFF7954-CA5E-410C-A7B2-1F1958B1C3A4Q34147052-97313A18-7C6B-4B75-A49A-6BA7B1E1C392Q34183686-F9ED0E5C-8EEF-450B-96F1-B57A934C42EDQ34196308-1F5A8D3C-A0A7-4C21-8054-39981C34EB83
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Stephen Beverley
@fr
Stephen M Beverley
@nl
Stephen M Beverley
@sl
Stephen M. Beverley
@en
Stephen M. Beverley
@es
type
label
Stephen Beverley
@fr
Stephen M Beverley
@nl
Stephen M Beverley
@sl
Stephen M. Beverley
@en
Stephen M. Beverley
@es
altLabel
Stephen Beverley
@en
Stephen M. Beverley
@en
prefLabel
Stephen Beverley
@fr
Stephen M Beverley
@nl
Stephen M Beverley
@sl
Stephen M. Beverley
@en
Stephen M. Beverley
@es
P106
P1153
7004527986
P21
P31
P496
0000-0001-5319-0811