Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes.
about
Linkage between the mechanisms of thrombocytopenia and thrombopoiesisEndoreplication and polyploidy: insights into development and diseaseMegakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiationNeonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition.Induction of megakaryocyte differentiation drives nuclear accumulation and transcriptional function of MKL1 via actin polymerization and RhoA activationMKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation.RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generationDefective endomitosis during megakaryopoiesis leads to thrombocytopenia in Fanca-/- mice.Manipulating megakaryocytes to manufacture platelets ex vivo.Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint.The incredible journey: From megakaryocyte development to platelet formation.Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells.Carboxyl-terminal-dependent recruitment of nonmuscle myosin II to megakaryocyte contractile ring during polyploidization.Cytosolic carboxypeptidase CCP6 is required for megakaryopoiesis by modulating Mad2 polyglutamylationHepatocytes polyploidization and cell cycle control in liver physiopathology.Presence of a defect in karyokinesis during megakaryocyte endomitosisCross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.Proplatelet generation in the mouse requires PKCε-dependent RhoA inhibition.Links between DNA Replication, Stem Cells and Cancer.Annexin V-induced rat Leydig cell proliferation involves Ect2 via RhoA/ROCK signaling pathway.Cell cycle regulation of Rho signaling pathways.Kinase signaling and targeted therapy for primary myelofibrosis.Progress in bio-manufacture of platelets for transfusion.Normal platelet counts mask abnormal thrombopoiesis in patients with chronic myeloid leukemia.Guanine nucleotide exchange factor H1 can be a new biomarker of melanoma.The Hippo-p53 pathway in megakaryopoiesis.PRMT1-RBM15 axis regulates megakaryocytic differentiation of human umbilical cord blood CD34+ cells.Mammalian endoreplication emerges to reveal a potential developmental timer.
P2860
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P2860
Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Role of RhoA-specific guanine ...... endomitosis in megakaryocytes.
@ast
Role of RhoA-specific guanine ...... endomitosis in megakaryocytes.
@en
type
label
Role of RhoA-specific guanine ...... endomitosis in megakaryocytes.
@ast
Role of RhoA-specific guanine ...... endomitosis in megakaryocytes.
@en
prefLabel
Role of RhoA-specific guanine ...... endomitosis in megakaryocytes.
@ast
Role of RhoA-specific guanine ...... endomitosis in megakaryocytes.
@en
P2093
P2860
P1433
P1476
Role of RhoA-specific guanine ...... endomitosis in megakaryocytes
@en
P2093
Diane S Krause
Ee-chun Cheng
Elenoe Smith
Phil Campbell
Sharon Lin
Siying Zou
Stephanie Halene
P2860
P304
P356
10.1016/J.DEVCEL.2011.12.019
P407
P577
2012-03-01T00:00:00Z