RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation
about
Megakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiationProteasome function is required for platelet productionLIM kinase/cofilin dysregulation promotes macrothrombocytopenia in severe von Willebrand disease-type 2B.Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation.Progress in understanding the diagnosis and molecular genetics of macrothrombocytopenias.Germline variants in ETV6 underlie reduced platelet formation, platelet dysfunction and increased levels of circulating CD34+ progenitors.Actin inhibition increases megakaryocyte proplatelet formation through an apoptosis-dependent mechanism.Regulation of actin polymerization by tropomodulin-3 controls megakaryocyte actin organization and platelet biogenesis.Kinase signaling and targeted therapy for primary myelofibrosis.The Hippo-p53 pathway in megakaryopoiesis.ROCK as a therapeutic target for ischemic stroke.Decreased thromboembolic stroke but not atherosclerosis or vascular remodelling in mice with ROCK2-deficient platelets.
P2860
Q28088519-1173AD29-7940-4916-85AC-356C9B3C91AFQ28244689-8A9CEBEB-0F07-41BC-ACD9-090D14825BC1Q30819316-34EC6A8A-FF2E-4343-BDBE-5399E322C037Q33413168-FE198E02-4902-48A4-9F4F-66BDE0DDE2E8Q33422572-00D4AD75-CC4D-4610-B273-1E34098F5F56Q33435561-8486F937-F7A9-473A-A092-0F0EA903D12EQ35416666-F77D0E1B-79F3-49BD-9B80-066B1FFB8BB5Q35884257-D428A1E5-9566-4082-80C9-212ED31EDF6AQ38775472-D9B4D8A9-7F67-46EB-B591-360DAFD5E2E6Q42335818-6A50A5FA-2D8B-48A5-B267-5C0961AFEEC4Q50066730-700879BB-A779-48F0-A7CA-82C0EB7D003CQ50710667-9053ED97-825C-46F9-A880-C15A5FB4FFF6
P2860
RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation
@ast
RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation
@en
type
label
RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation
@ast
RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation
@en
prefLabel
RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation
@ast
RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation
@en
P2093
P2860
P1433
P1476
RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation
@en
P2093
Aae Suzuki
Charles S Abrams
Chris L Carpenter
Jae-Won Shin
John K Choi
Liang Zhao
Lurong Lian
Morty Poncz
Sang H Min
Yangfeng Wang
P2860
P304
P356
10.1371/JOURNAL.PONE.0069315
P407
P577
2013-07-23T00:00:00Z