FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels - Wikidata - wikimedia - TriplyDB

FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels

FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels

http://www.wikidata.org/entity/Q30536899

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The Presynaptic Microtubule Cytoskeleton in Physiological and Pathological Conditions: Lessons from Drosophila Fragile X Syndrome and Hereditary Spastic Paraplegias Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome RNA Secondary Structure Modulates FMRP's Bi-Functional Role in the MicroRNA Pathway Proteostasis and RNA Binding Proteins in Synaptic Plasticity and in the Pathogenesis of Neuropsychiatric Disorders Single-Nucleotide Mutations in FMR1 Reveal Novel Functions and Regulatory Mechanisms of the Fragile X Syndrome Protein FMRP Moving from capstones toward cornerstones: successes and challenges in applying systems biology to identify mechanisms of autism spectrum disorders Dysregulation and restoration of translational homeostasis in fragile X syndrome Genetic disruption of voltage-gated calcium channels in psychiatric and neurological disorders Altered Neuronal and Circuit Excitability in Fragile X Syndrome.Synaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia.BK channels: multiple sensors, one activation gate Channelopathy pathogenesis in autism spectrum disorders Channelopathies and dendritic dysfunction in fragile X syndrome.Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes Mice with deficient BK channel function show impaired prepulse inhibition and spatial learning, but normal working and spatial reference memory.The sodium-activated potassium channel Slack is required for optimal cognitive flexibility in mice Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back Insulin-Like Growth Factor 1 and Related Compounds in the Treatment of Childhood-Onset Neurodevelopmental Disorders mTOR and MAPK: from localized translation control to epilepsy Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density Novel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticity Sensory processing in autism spectrum disorders and Fragile X syndrome-From the clinic to animal models.BK Channels in the Central Nervous System.Matrix metalloproteinase-9 deletion rescues auditory evoked potential habituation deficit in a mouse model of Fragile X Syndrome GABA receptor subunit distribution and FMRP-mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism.In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome From FMRP function to potential therapies for fragile X syndrome.Habituation of reflexive and motivated behavior in mice with deficient BK channel function.Activity-dependent regulation of release probability at excitatory hippocampal synapses: a crucial role of fragile X mental retardation protein in neurotransmission Emerging role of the KCNT1 Slack channel in intellectual disability.Modulation of the GABAergic pathway for the treatment of fragile X syndrome.N-myristoylation regulates the axonal distribution of the Fragile X-related protein FXR2P Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by a BKCa channel opener molecule.More than a pore: ion channel signaling complexes Molecular Advances Leading to Treatment Implications for Fragile X Premutation Carriers Human slack potassium channel mutations increase positive cooperativity between individual channels Shaping synaptic learning by the duration of postsynaptic action potential in a new STDP model.Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain.

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FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels

http://www.wikidata.org/entity/Q30536899

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2013 nî lūn-bûn

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2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի փետրվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

FMRP regulates neurotransmitte ...... ntial duration via BK channels

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FMRP regulates neurotransmitte ...... ntial duration via BK channels

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type

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FMRP regulates neurotransmitte ...... ntial duration via BK channels

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FMRP regulates neurotransmitte ...... ntial duration via BK channels

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FMRP regulates neurotransmitte ...... ntial duration via BK channels

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FMRP regulates neurotransmitte ...... ntial duration via BK channels

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FMRP regulates neurotransmitte ...... ntial duration via BK channels

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Jay A Blundon

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Jianmin Cui

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Pan-Yue Deng

http://www.w3.org/2001/XMLSchema#string

Valeria Cavalli

http://www.w3.org/2001/XMLSchema#string

Vitaly A Klyachko

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Yongcheol Cho

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Ziv Rotman

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P2860

The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction

Altered synaptic plasticity in a mouse model of fragile X mental retardation

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structure

The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat

Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome

Dysregulation of presynaptic calcium and synaptic plasticity in a mouse model of 22q11 deletion syndrome.

Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release

The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits

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4

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Stanislav S. Zakharenko

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2013-02-01T00:00:00Z

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235728783

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neurotransmitter

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3584349

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