about
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesisRequirement of RIZ1 for cancer prevention by methyl-balanced dietIsolation and preliminary characterization of the transforming gene of a human neuroblastoma cell lineMost human carcinomas of the exocrine pancreas contain mutant c-K-ras genesAnalysis of genetic variability and mapping of point mutations in influenza virus by the RNase A mismatch cleavage methodDNA demethylation in normal colon tissue predicts predisposition to multiple cancers.A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis.Prognostic significance of apoptosis regulators in breast cancer.DNA methylation alterations of AXIN2 in serrated adenomas and colon carcinomas with microsatellite instability.Down-regulation of epidermal growth factor receptor by selective expansion of a 5'-end regulatory dinucleotide repeat in colon cancer with microsatellite instability.Functional significance of concomitant inactivation of hMLH1 and hMSH6 in tumor cells of the microsatellite mutator phenotype.Microsatellite instability and ploidy status define three categories with distinctive prognostic impact in endometrioid endometrial cancerHuman-tumor-derived cell lines contain common and different transforming genes.Isolation of the chicken thymidine kinase gene by plasmid rescue.Transformation of mammalian cells with an amplifiable dominant-acting gene.Genetic and physical linkage of exogenous sequences in transformed cells.The somatic replication of DNA methylation.Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells.Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability.Gastrointestinal cancer of the microsatellite mutator phenotype pathway.Substrate cleavage profiling suggests a distinct function of Bacteroides fragilis metalloproteinases (fragilysin and metalloproteinase II) at the microbiome-inflammation-cancer interface.Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors.Chromatin structure of the promoter region of the human c-K-ras geneActivation of a human c-K-ras oncogeneMethylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans.Somatic DNA Hypomethylation in H. pylori-Associated High-Risk Gastritis and Gastric Cancer: Enhanced Somatic Hypomethylation Associates with Advanced Stage Cancer.International conference on the healthy effect of virgin olive oil.Mycoplasma CG- and GATC-specific DNA methyltransferases selectively and efficiently methylate the host genome and alter the epigenetic landscape in human cells.A comprehensive custom panel design for routine hereditary cancer testing: preserving control, improving diagnostics and revealing a complex variation landscapeIsolation of transforming sequences of two human lung carcinomas: structural and functional analysis of the activated c-K-ras oncogenes.Molecular karyotype (amplotype) of metastatic colorectal cancer by unbiased arbitrarily primed PCR DNA fingerprinting.Moderate amplifications of the c-myc gene correlate with molecular and clinicopathological parameters in colorectal cancer.Epigenetic inactivation of the extracellular matrix metallopeptidase ADAMTS19 gene and the metastatic spread in colorectal cancer.Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma.Array-based identification of common DNA methylation alterations in ulcerative colitisGenetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas.Expression of the Kirsten ras viral and human proteins in Escherichia coli.Inhibitory effect of interferon on the genetic and oncogenic transformation by viral and cellular genes.Oncogene amplification during tumorigenesis of established rat fibroblasts reversibly transformed by activated human ras oncogenesQuantification of unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples
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P50
description
hulumtues
@sq
researcher
@en
հետազոտող
@hy
name
Manuel Perucho
@ast
Manuel Perucho
@en
Manuel Perucho
@es
Manuel Perucho
@fr
Manuel Perucho
@nl
Manuel Perucho
@sl
type
label
Manuel Perucho
@ast
Manuel Perucho
@en
Manuel Perucho
@es
Manuel Perucho
@fr
Manuel Perucho
@nl
Manuel Perucho
@sl
prefLabel
Manuel Perucho
@ast
Manuel Perucho
@en
Manuel Perucho
@es
Manuel Perucho
@fr
Manuel Perucho
@nl
Manuel Perucho
@sl
P108
P108
P21
P31
P496
0000-0002-2169-2662