Isolation of transforming sequences of two human lung carcinomas: structural and functional analysis of the activated c-K-ras oncogenes.
about
A novel combination of K-ras and myc amplification accompanied by point mutational activation of K-ras in a human lung cancerActivation of an N-ras gene in acute myeloblastic leukemia through somatic mutation in the first exonCDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.Ras oncogenes: split personalitiesUtilizing protein structure to identify non-random somatic mutations.DNA analysis in human diseaseNeurospora crassa cDNA clones coding for a new member of the ras protein family.Expression of normal and transforming H-ras genes in Escherichia coli and purification of their encoded p21 proteins.Cooperation of c-raf-1 and c-myc protooncogenes in the neoplastic transformation of simian virus 40 large tumor antigen-immortalized human bronchial epithelial cells.Oncogenes and tumor-suppressor genes.Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy.Chromatin structure of the promoter region of the human c-K-ras geneNew routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing.Activation of a human c-K-ras oncogeneDetection and identification of activated oncogenes in spontaneously occurring benign and malignant hepatocellular tumors of the B6C3F1 mouse.Mutations activating human c-Ha-ras1 protooncogene (HRAS1) induced by chemical carcinogens and depurination.Enhanced c-Ki-ras expression associated with Friend virus integration in a bone marrow-derived mouse cell line.Mycoplasma CG- and GATC-specific DNA methyltransferases selectively and efficiently methylate the host genome and alter the epigenetic landscape in human cells.Moderate amplifications of the c-myc gene correlate with molecular and clinicopathological parameters in colorectal cancer.Transgenic mice carrying the mouse mammary tumor virus ras fusion gene: distinct effects in various tissues.Personalizing therapy in advanced non-small cell lung cancerInhibitory effect of interferon on the genetic and oncogenic transformation by viral and cellular genes.Activation of ras p21 transforming properties associated with an increase in the release rate of bound guanine nucleotide.A human Ki-ras oncogene encodes two transforming p21 proteinsOncogene amplification during tumorigenesis of established rat fibroblasts reversibly transformed by activated human ras oncogenesIsolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reactionDetection of a raf-related and two other transforming DNA sequences in human tumors maintained in nude miceA method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cellsMolecular cloning and the total nucleotide sequence of the human c-Ha-ras-1 gene activated in a melanoma from a Japanese patient.Guanosine nucleotide binding by highly purified Ha-ras-encoded p21 protein produced in Escherichia coli.Ha-ras proteins exhibit GTPase activity: point mutations that activate Ha-ras gene products result in decreased GTPase activity.Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surfaceMolecular pathways: microRNAs as cancer therapeutics.Retroviruses and human cancer: evaluation of T-lymphocyte transformation by human T-cell leukemia-lymphoma virus.Human cancer and cellular oncogenes.Three different mutations in codon 61 of the human N-ras gene detected by synthetic oligonucleotide hybridization.Four human carcinoma cell lines with novel mutations in position 12 of c-K-ras oncogene.Ras2 and Ras1 protein phosphorylation in Saccharomyces cerevisiae.Understanding and targeting resistance mechanisms in NSCLC.
P2860
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P2860
Isolation of transforming sequences of two human lung carcinomas: structural and functional analysis of the activated c-K-ras oncogenes.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Isolation of transforming sequ ...... e activated c-K-ras oncogenes.
@ast
Isolation of transforming sequ ...... e activated c-K-ras oncogenes.
@en
type
label
Isolation of transforming sequ ...... e activated c-K-ras oncogenes.
@ast
Isolation of transforming sequ ...... e activated c-K-ras oncogenes.
@en
prefLabel
Isolation of transforming sequ ...... e activated c-K-ras oncogenes.
@ast
Isolation of transforming sequ ...... e activated c-K-ras oncogenes.
@en
P2093
P2860
P356
P1476
Isolation of transforming sequ ...... he activated c-K-ras oncogenes
@en
P2093
P2860
P356
10.1073/PNAS.81.1.71
P407
P577
1984-01-01T00:00:00Z