α-Synuclein oligomers impair neuronal microtubule-kinesin interplay. - Wikidata - wikimedia - TriplyDB

α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

http://www.wikidata.org/entity/Q30541822

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Unfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion Diseases Αlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's Disease The Diagnostic and Differential Diagnosis Utility of Cerebrospinal Fluid α -Synuclein Levels in Parkinson's Disease: A Meta-Analysis The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease Adult hippocampal neurogenesis in Parkinson's disease: impact on neuronal survival and plasticity Seeking a mechanism for the toxicity of oligomeric α-synuclein Dysfunction of spatacsin leads to axonal pathology in SPG11-linked hereditary spastic paraplegia Alpha-synuclein and tau: teammates in neurodegeneration?α-Synuclein is a Novel Microtubule Dynamase.Cutaneous neuropathy in Parkinson's disease: a window into brain pathology.α-Synuclein binds to the ER-mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production Novel AAV-based rat model of forebrain synucleinopathy shows extensive pathologies and progressive loss of cholinergic interneurons β-III Tubulin fragments inhibit α-synuclein accumulation in models of multiple system atrophy.Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats.Acteoside Binds to Caspase-3 and Exerts Neuroprotection in the Rotenone Rat Model of Parkinson's Disease.Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons.Activation of Mitochondrial Complex II-Dependent Respiration Is Beneficial for α-Synucleinopathies.Blood Plasma of Patients with Parkinson's Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity.Back to the tubule: microtubule dynamics in Parkinson's disease.Tau protein modifications and interactions: their role in function and dysfunction.Oligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders?Structure, function and toxicity of alpha-synuclein: the Bermuda triangle in synucleinopathies.Impairment of mitochondria dynamics by human A53T α-synuclein and rescue by NAP (davunetide) in a cell model for Parkinson's disease.HIV-1 Vpr disrupts mitochondria axonal transport and accelerates neuronal aging.Microtubule Destabilization Paves the Way to Parkinson's Disease.Neurotrophin Signaling and Stem Cells-Implications for Neurodegenerative Diseases and Stem Cell Therapy.αSynuclein control of mitochondrial homeostasis in human-derived neurons is disrupted by mutations associated with Parkinson's disease.Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice.Mitochondrial dynamics in Parkinson's disease: a role for α-synuclein?Extracellular ATP induces intracellular alpha-synuclein accumulation via P2X1 receptor-mediated lysosomal dysfunction.Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice.Alpha-synuclein oligomers: a new hope.The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity.Current perspective of mitochondrial biology in Parkinson's disease.The direct and indirect effects of α-synuclein on microtubule stability in the pathogenesis of Parkinson's disease.α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies

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α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

http://www.wikidata.org/entity/Q30541822

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2013 nî lūn-bûn

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2013 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2013 թվականի հունիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

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α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

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α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

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α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

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α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

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α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

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JBC.M113.451815

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Journal of Biological Chemistry

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α-Synuclein oligomers impair neuronal microtubule-kinesin interplay

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Katrin Buder

http://www.w3.org/2001/XMLSchema#string

Konrad J Böhm

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Roland Riek

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Silvia Campioni

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Stefanie Brey

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Vanesa Veber

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A protein factor essential for microtubule assembly

Tubulin seeds alpha-synuclein fibril formation

Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity

alpha-Synuclein and its disease-related mutants interact differentially with the microtubule protein tau and associate with the actin cytoskeleton

Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models

Molecular motors implicated in the axonal transport of tau and alpha-synuclein

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

alpha-Synuclein locus triplication causes Parkinson's disease

Alpha-synuclein in Lewy bodies

Microtubule acetylation promotes kinesin-1 binding and transport.

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