The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance - Wikidata - wikimedia - TriplyDB

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

http://www.wikidata.org/entity/Q30547080

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Different role of zinc transporter 8 between type 1 diabetes mellitus and type 2 diabetes mellitus The Functions of Metallothionein and ZIP and ZnT Transporters: An Overview and Perspective Zinc and diabetes mellitus: understanding molecular mechanisms and clinical implications Zinc transporter 8 (ZnT8) and β cell function SLC transporters as therapeutic targets: emerging opportunities Roles of Zinc Signaling in the Immune System Pharmacogenomics in diabetes mellitus: insights into drug action and drug discovery Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application.Exploring the Association Between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and Nickel Loss-of-function mutations in SLC30A8 protect against type 2 diabetes Molecular pathogenesis of spondylocheirodysplastic Ehlers-Danlos syndrome caused by mutant ZIP13 proteins.Physiological roles of zinc transporters: molecular and genetic importance in zinc homeostasis.TCF7L2 is a master regulator of insulin production and processing.Altered pancreatic growth and insulin secretion in WSB/EiJ mice.The physiological role of drug transporters.Endurance training inhibits insulin clearance and IDE expression in Swiss mice.Association between SLC30A8 rs13266634 Polymorphism and Type 2 Diabetes Risk: A Meta-Analysis.Glucose Homeostatic Law: Insulin Clearance Predicts the Progression of Glucose Intolerance in Humans.Effect of zinc supplementation on insulin secretion: interaction between zinc and SLC30A8 genotype in Old Order Amish.Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: ROLES IN REGULATING CYTOSOLIC ZINC HOMEOSTASIS AND INSULIN SECRETION.The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion.Pulsatile insulin secretion, impaired glucose tolerance and type 2 diabetes.Over-expression of Slc30a8/ZnT8 selectively in the mouse α cell impairs glucagon release and responses to hypoglycemia.Molecular Genetic Regulation of Slc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance.Serum Zn/Cu Ratio Is Associated with Renal Function, Glycemic Control, and Metabolic Parameters in Japanese Patients with and without Type 2 Diabetes: A Cross-sectional Study.Lack of Association between SLC30A8 Variants and Type 2 Diabetes in Mexican American Families.Pancreatic β cell identity requires continual repression of non-β cell programs.Zinc-rs13266634 and the arrival of diabetes pharmacogenetics: the "zinc mystique"Targeting the pancreatic β-cell to treat diabetes.Current understanding of ZIP and ZnT zinc transporters in human health and diseases.Dorothy Hodgkin Lecture 2014. Understanding genes identified by genome-wide association studies for type 2 diabetes.IRS2 integrates insulin/IGF1 signalling with metabolism, neurodegeneration and longevity.SLC30A8 mutations in type 2 diabetes.Beta cell connectivity in pancreatic islets: a type 2 diabetes target?Pharmacogenomics of glinides.The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism.Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression Protective alleles and modifier variants in human health and disease.The zinc transporter ZNT3 co-localizes with insulin in INS-1E pancreatic beta cells and influences cell survival, insulin secretion capacity, and ZNT8 expression.Does Zinc Really "Metal" with Diabetes? The Epidemiologic Evidence.

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The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

http://www.wikidata.org/entity/Q30547080

description

2013 nî lūn-bûn

@nan

2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

@ast

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

@en

type

label

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

@ast

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

@en

prefLabel

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

@ast

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

@en

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P1433

Journal of Clinical Investigation

P1476

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

@en

P2093

Akemi Hara

http://www.w3.org/2001/XMLSchema#string

Akio Kanazawa

http://www.w3.org/2001/XMLSchema#string

Ayako Fukunaka

http://www.w3.org/2001/XMLSchema#string

Hiroshi Kiyonari

http://www.w3.org/2001/XMLSchema#string

Kageumi Takeno

http://www.w3.org/2001/XMLSchema#string

Mica O Imaizumi

http://www.w3.org/2001/XMLSchema#string

Minako Kawaguchi

http://www.w3.org/2001/XMLSchema#string

Motoyuki Tamaki

http://www.w3.org/2001/XMLSchema#string

Ryuzo Kawamori

http://www.w3.org/2001/XMLSchema#string

Shintaro Hojyo

http://www.w3.org/2001/XMLSchema#string

P2860

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

The physiological effects of deleting the mouse SLC30A8 gene encoding zinc transporter-8 are influenced by gender and genetic background

Structure of the zinc transporter YiiP

Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of Insulin

Glucagon receptors on human islet cells contribute to glucose competence of insulin release

CEACAM1 regulates insulin clearance in liver

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

GPR39 signaling is stimulated by zinc ions but not by obestatin

Insulin degradation: progress and potential

P304

4513-4524

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scholarly article

P356

10.1172/JCI68807

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P407

P433

10

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P478

123

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Takeshi Kawauchi

Hirotaka Watada

P577

2013-09-24T00:00:00Z

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24051378

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P932

3784536

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