Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse. - Wikidata - wikimedia - TriplyDB

Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse.

Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse.

http://www.wikidata.org/entity/Q30582830

about

Systems biology of coagulation Genotyping and phenotyping of platelet function disorders Mechanisms of fibrin polymerization and clinical implications The platelet and the biophysical microenvironment: lessons from cellular mechanics Microfluidics and coagulation biology The effect of factor VIII deficiencies and replacement and bypass therapies on thrombus formation under venous flow conditions in microfluidic and computational models TACTIC: Trans-Agency Consortium for Trauma-Induced Coagulopathy In microfluidico: Recreating in vivo hemodynamics using miniaturized devices A human platelet calcium calculator trained by pairwise agonist scanning Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network.Membrane Ballooning in Aggregated Platelets is Synchronised and Mediates a Surge in Microvesiculation.Multiscale simulation of thrombus growth and vessel occlusion triggered by collagen/tissue factor using a data-driven model of combinatorial platelet signalling.A systems approach to hemostasis: 1. The interdependence of thrombus architecture and agonist movements in the gaps between platelets.A systems approach to hemostasis: 2. Computational analysis of molecular transport in the thrombus microenvironment.Shaping the platelet response to vascular injury.Real-time measurement of thrombin generation using continuous droplet microfluidics Fibrin networks regulate protein transport during thrombus development Defective release of α granule and lysosome contents from platelets in mouse Hermansky-Pudlak syndrome models.FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow Non-invasive imaging and cellular tracking of pulmonary emboli by near-infrared fluorescence and positron-emission tomography.Microfluidic whole blood testing of platelet response to pharmacological agents.Mutant B-Raf(V600E) Promotes Melanoma Paracellular Transmigration by Inducing Thrombin-mediated Endothelial Junction Breakdown A systems approach to hemostasis: 4. How hemostatic thrombi limit the loss of plasma-borne molecules from the microvasculature.Systems Analysis of Thrombus Formation.Side view thrombosis microfluidic device with controllable wall shear rate and transthrombus pressure gradient.Microfluidic assay of hemophilic blood clotting: distinct deficits in platelet and fibrin deposition at low factor levels.The effects of arterial flow on platelet activation, thrombus growth, and stabilization.Platelet secretion: From haemostasis to wound healing and beyond.Fluid Mechanics of Blood Clot Formation.Spatiotemporal regulation of coagulation and platelet activation during the hemostatic response in vivo.Transport physics and biorheology in the setting of hemostasis and thrombosis.Probing for thiol isomerase activity in thrombi.Minimum wound size for clotting: flowing blood coagulates on a single collagen fiber presenting tissue factor and von Willebrand factor.Contact activation of blood coagulation on a defined kaolin/collagen surface in a microfluidic assay.Fibrin, γ'-fibrinogen, and transclot pressure gradient control hemostatic clot growth during human blood flow over a collagen/tissue factor wound.Dynamics of Thrombin Generation and Flux from Clots during Whole Human Blood Flow over Collagen/Tissue Factor Surfaces.Probing the Dynamics of Clot-Bound Thrombin at Venous Shear Rates.Hierarchical organization of the hemostatic response to penetrating injuries in the mouse macrovasculature.Inhibition of protease-activated receptor 4 impairs platelet procoagulant activity during thrombus formation in human blood.Functional cyclophilin D moderates platelet adhesion, but enhances the lytic resistance of fibrin.

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P2860

Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse.

http://www.wikidata.org/entity/Q30582830

description

2012 nî lūn-bûn

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2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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Platelet-targeting sensor reve ...... rofluidic assays and in mouse.

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Platelet-targeting sensor reve ...... rofluidic assays and in mouse.

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Platelet-targeting sensor reve ...... rofluidic assays and in mouse.

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J.1538-7836.2012.04928.X

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Journal of Thrombosis and Haemostasis

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Platelet-targeting sensor reve ...... rofluidic assays and in mouse.

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J D Welsh

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L F Brass

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R W Muthard

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S L Diamond

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T J Stalker

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P2860

Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha

Calibrated automated thrombin generation measurement in clotting plasma

Surface-mediated control of blood coagulation: the role of binding site densities and platelet deposition

Endothelial cell specific adhesion molecule (ESAM) localizes to platelet-platelet contacts and regulates thrombus formation in vivo

Inflammation, sepsis, and coagulation.

Systems biology of coagulation initiation: kinetics of thrombin generation in resting and activated human blood.

Thrombin flux and wall shear rate regulate fibrin fiber deposition state during polymerization under flow.

Evaluation of methodologies for measurement of interstitial fluid pressure (Pi): physiological implications of recent Pi data.

Engineering design of optimal strategies for blood clot dissolution.

Factor XI activation in a revised model of blood coagulation.

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