Cutting edge: cell surface linker for activation of T cells is recruited to microclusters and is active in signaling - Wikidata - wikimedia - TriplyDB

Cutting edge: cell surface linker for activation of T cells is recruited to microclusters and is active in signaling

Cutting edge: cell surface linker for activation of T cells is recruited to microclusters and is active in signaling

http://www.wikidata.org/entity/Q30586313

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New Insights into How Trafficking Regulates T Cell Receptor Signaling Comparative Anatomy of Phagocytic and Immunological Synapses Regulated vesicle fusion generates signaling nanoterritories that control T cell activation at the immunological synapse.Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamics A large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals.TCR Microclusters pre-exist and contain molecules necessary for TCR signal transduction.Phase transitions of multivalent proteins can promote clustering of membrane receptors The ability of Sos1 to oligomerize the adaptor protein LAT is separable from its guanine nucleotide exchange activity in vivo.Human Serum Albumin (HSA) Suppresses the Effects of Glycerol Monolaurate (GML) on Human T Cell Activation and Function.IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo Glycerol Monolaurate (GML) inhibits human T cell signaling and function by disrupting lipid dynamics.A large Rab GTPase family in a small GTPase world Wiskott-Aldrich syndrome protein--dynamic regulation of actin homeostasis: from activation through function and signal termination in T lymphocytes.Orchestrating cytoskeleton and intracellular vesicle traffic to build functional immunological synapses.Tracking single molecules at work in living cells.Integrative biology of T cell activation.Signaling at the immune synapse: vesicular trafficking takes the stage.Reconstitution of TCR Signaling Using Supported Lipid Bilayers.Membrane lipid order of sub-synaptic T cell vesicles correlates with their dynamics and function.Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation.Purification of LAT-Containing Membranes from Resting and Activated T Lymphocytes.Glycerol monolaurate induces filopodia formation by disrupting the association between LAT and SLP-76 microclusters.Membrane nanodomains in T-cell antigen receptor signalling.Macromolecular assembly of the adaptor SLP-65 at intracellular vesicles in resting B cells.Plasma membrane LAT activation precedes vesicular recruitment defining two phases of early T-cell activation.

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Cutting edge: cell surface linker for activation of T cells is recruited to microclusters and is active in signaling

http://www.wikidata.org/entity/Q30586313

description

2013 nî lūn-bûn

@nan

2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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2013年学术文章

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2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

name

Cutting edge: cell surface lin ...... ers and is active in signaling

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Cutting edge: cell surface lin ...... ers and is active in signaling

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Cutting edge: cell surface lin ...... ers and is active in signaling

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Cutting edge: cell surface lin ...... ers and is active in signaling

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Cutting edge: cell surface lin ...... ers and is active in signaling

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Cutting edge: cell surface lin ...... ers and is active in signaling

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P356

JIMMUNOL.1202760

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Journal of Immunology

P1476

Cutting edge: cell surface lin ...... ers and is active in signaling

@en

P2093

Anna K Park

http://www.w3.org/2001/XMLSchema#string

Lakshmi Balagopalan

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Lawrence E Samelson

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Robert L Kortum

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Valarie A Barr

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P2860

Dissecting T-cell activation with high-resolution live-cell microscopy

Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

c-Cbl-mediated regulation of LAT-nucleated signaling complexes

T cell activation at the immunological synapse: vesicles emerge for LATer signaling.

Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse.

Markers for detergent-resistant lipid rafts occupy distinct and dynamic domains in native membranes.

Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways.

Functional nanoscale organization of signaling molecules downstream of the T cell antigen receptor.

TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation.

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3849-3853

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scholarly article

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10.4049/JIMMUNOL.1202760

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8

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190

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2013-03-13T00:00:00Z

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23487428

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4144449

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