Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
about
The role of lipids in mechanosensation.Engineered transmembrane pores.Identification of a Membrane-bound Prepore Species Clarifies the Lytic Mechanism of ActinoporinsAssembling the puzzle: Oligomerization of α-pore forming proteins in membranesCharacterization of the Lipid-Binding Site of Equinatoxin II by NMR and Molecular Dynamics SimulationSphingomyelin is sorted at the trans Golgi network into a distinct class of secretory vesicle.Evolution of the Cytolytic Pore-Forming Proteins (Actinoporins) in Sea Anemones.More Than a Pore: The Interplay of Pore-Forming Proteins and Lipid Membranes.Electron Cryo-microscopy as a Tool for Structure-Based Drug Development.Disrupting a key hydrophobic pair in the oligomerization interface of the actinoporins impairs their pore-forming activity.Ostreolysin A/Pleurotolysin B and Equinatoxins: Structure, Function and Pathophysiological Effects of These Pore-Forming Proteins.Single-molecule nanopore enzymology.A pore-forming toxin requires a specific residue for its activity in membranes with particular physicochemical properties.Enhanced imaging of lipid rich nanoparticles embedded in methylcellulose films for transmission electron microscopy using mixtures of heavy metals.Functional characterization of Val60, a key residue involved in the membrane-oligomerization of fragaceatoxin C, an actinoporin from Actinia fragacea.Synergistic Action of Actinoporin Isoforms from the Same Sea Anemone Species Assembled into Functionally Active Heteropores.Recombinant production and affinity purification of the FraC pore forming toxin using hexa-His tag and pET expression cassette.Electro-osmotic capture and ionic discrimination of peptide and protein biomarkers with FraC nanopores.Biophysical and biochemical strategies to understand membrane binding and pore formation by sticholysins, pore-forming proteins from a sea anemone.Alpha-Helical Fragaceatoxin C Nanopore Engineered for Double-Stranded and Single-Stranded Nucleic Acid Analysis.Topography of the TH5 Segment in the Diphtheria Toxin T-Domain Channel.Haemolytic actinoporins interact with carbohydrates using their lipid-binding module.Disruption of the open conductance in the β-tongue mutants of Cytolysin A.A novel microseeding method for the crystallization of membrane proteins in lipidic cubic phase.Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB.Self-homodimerization of an actinoporin by disulfide bridging reveals implications for their structure and pore formation.Multigene Family of Pore-Forming Toxins from Sea Anemone Heteractis crispa.Membrane insertion of α-xenorhabdolysin in near-atomic detailModular pore-forming immunotoxins with caged cytotoxicity tailored by directed evolutionKryo-Elektronenmikroskopie als Methode für die strukturbasierte WirkstoffentwicklungStructural and Mechanistic Features of ClyA-Like α-Pore-Forming Toxins
P2860
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P2860
Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
@ast
Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
@en
type
label
Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
@ast
Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
@en
prefLabel
Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
@ast
Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
@en
P2860
P50
P356
P1476
Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
@en
P2093
Koji Tanaka
Kouhei Tsumoto
P2860
P2888
P356
10.1038/NCOMMS7337
P407
P577
2015-02-26T00:00:00Z
P6179
1035126277