about
Testing Geometrical Discrimination within an Enzyme Active Site: Constrained Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion HoleHydrogen Bond Coupling in the Ketosteroid Isomerase Active SiteMolecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureusCrystal structure of the enzyme CapF of Staphylococcus aureus reveals a unique architecture composed of two functional domainsCrystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureusSelective binding of antimicrobial porphyrins to the heme-receptor IsdH-NEAT3 ofStaphylococcus aureusQuantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active siteIncorporation of rapid thermodynamic data in fragment-based drug discoveryDynamic elements govern the catalytic activity of CapE, a capsular polysaccharide-synthesizing enzyme from Staphylococcus aureusThermodynamic and structural characterization of the specific binding of Zn(II) to human protein DJ-1Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureusBidirectional Transformation of a Metamorphic Protein between the Water-Soluble and Transmembrane Native StatesAdhesive Dimerization of Human P-Cadherin Catalyzed by a Chaperone-like MechanismIdentification of a Membrane-bound Prepore Species Clarifies the Lytic Mechanism of ActinoporinsMapping ultra-weak protein-protein interactions between heme transporters of Staphylococcus aureusStructural basis for self-assembly of a cytolytic pore lined by protein and lipidDetection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase.Solubilization of membrane proteins with novel N-acylamino acid detergents.The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External RegionStructural and Thermodynamic Basis of Epitope Binding by Neutralizing and Nonneutralizing Forms of the Anti-HIV-1 Antibody 4E10.Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface.Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin.Structural analysis of Fc/FcγR complexes: a blueprint for antibody design.Peripheral Membrane Interactions Boost the Engagement by an Anti-HIV-1 Broadly Neutralizing Antibody.Glycosylation of IgG-Fc: a molecular perspective.Non-core region modulates interleukin-11 signaling activity: generation of agonist and antagonist variants.Contributions of interfacial residues of human Interleukin15 to the specificity and affinity for its private alpha-receptor.A pore-forming toxin requires a specific residue for its activity in membranes with particular physicochemical properties.Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane.Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI.Functional characterization of Val60, a key residue involved in the membrane-oligomerization of fragaceatoxin C, an actinoporin from Actinia fragacea.In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis.Affinity improvement of a therapeutic antibody by structure-based computational design: generation of electrostatic interactions in the transition state stabilizes the antibody-antigen complex.Reply to "The Broadly Neutralizing, Anti-HIV Antibody 4E10: an Open and Shut Case?".Binding of hydrophobic hydroxamic acids enhances peroxidase's stereoselectivity in nonaqueous sulfoxidations.Identification and characterization of the X-dimer of human P-cadherin: implications for homophilic cell adhesion.Asymmetric sulfoxidations mediated by alpha-chymotrypsin.Differential Effect of Membrane Composition on the Pore-Forming Ability of Four Different Sea Anemone Actinoporins.Lipid phase coexistence favors membrane insertion of equinatoxin-II, a pore-forming toxin from Actinia equina.Haemolytic actinoporins interact with carbohydrates using their lipid-binding module.
P50
Q27652268-9B337F8A-C75C-4EC1-960A-DFFB92ECC6E4Q27655611-6CBD9BC2-DBAC-4991-AD13-1EFFC5C8E089Q27671122-F301A95C-0202-4A2C-BF1A-359CE946652BQ27677173-DF0678D5-BE7C-4005-A9E2-59C99AC48967Q27677521-9AD4BFE6-383E-423A-AF9A-F3CDEE57FDDAQ27678015-707FBFAE-A7A9-4BAD-9B5B-55A33B549C8FQ27678764-736ADF69-ED7E-4886-BA7B-6E54DBBD4DC7Q27684035-DB149260-9D18-4C59-B568-B613FDA995D3Q27687348-8198385F-11F9-4825-B070-95D316FFBBB5Q27689686-B02EC172-DE4A-4A1E-B7E6-0FFBBD999B1AQ27702303-AEC75E25-C020-4ECE-A3BF-1F4E911BB7EEQ27702578-4D3BFF8C-86D0-4914-9C71-A844046611E6Q27727724-8A2239C5-4FB3-4CD5-8B0B-72BF7B12EBB4Q30390842-8F275062-DF8F-4F0D-8462-9E8A173FFCC8Q30514059-BDEB4999-733B-4C1B-B2F9-25CF27A2DD74Q30625306-9485FBAF-3A15-4496-B87B-53DF979C8229Q33466833-C9315726-8F82-4363-8F61-522018F1B3E6Q33541871-456E662C-0CC5-4122-9D9A-0FE94E70A42AQ35860914-F3592FDF-00CA-44DA-BAAA-EB311FE264E3Q36281210-0EAAE1B6-6711-452E-86BA-9C74CD5121FBQ37459903-495F21B2-EA72-43EA-B4C1-D93FCD53249BQ37550559-6C93EFF2-A06D-49AC-AFDC-959B8DDC399FQ38615376-95F5F15B-8016-467A-A67A-9CA0C96CD7FBQ38954558-24139683-3A26-4089-9EB4-D9C41BD021F8Q39401108-840F57BF-C90D-458D-AB4B-A96373F286ECQ39622839-FAE9CC25-BFA2-4B06-925C-C7FF53CACBBFQ39858411-B27401BD-23F3-45CA-884B-F12B14D1E5A2Q39944610-D1FCC487-8909-4619-9881-686BDC646A10Q40289677-145306A0-B62C-4052-96AA-0FD111605E3EQ40388373-71CCBD55-E2B2-4980-9C1F-A06570D26904Q40813866-9DBD8FE3-A745-424C-BD5F-E059D1FF4CEEQ40989137-DC629653-90EC-45C2-9EC4-61B2DEFE375AQ41894132-3045CF11-DB4C-4C71-A5DB-5FDAE1716EAFQ42551527-8DACF9F8-3B34-4E9B-B9CA-94E940581CFBQ43870974-A7A29CEF-A67A-4A17-A627-3DABB7FF7A65Q43913353-893D7E0F-88F8-487B-A7FE-80F88092C7FBQ45714351-F897E103-E834-4B31-A166-CCCE4981A93EQ46448555-B68624EF-11BC-4FD1-9A8F-B4C0F1F8B2BFQ47400608-DCF2F7AC-7D39-4A40-A499-98A2DACAEE91Q50935628-045256EB-6D29-4397-9344-1C12F3C28158
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jose M.m. Caaveiro
@ast
Jose M.m. Caaveiro
@en
Jose M.m. Caaveiro
@es
Jose M.m. Caaveiro
@nl
Jose M.m. Caaveiro
@sl
type
label
Jose M.m. Caaveiro
@ast
Jose M.m. Caaveiro
@en
Jose M.m. Caaveiro
@es
Jose M.m. Caaveiro
@nl
Jose M.m. Caaveiro
@sl
altLabel
Jose M.M. Caaveiro
@en
prefLabel
Jose M.m. Caaveiro
@ast
Jose M.m. Caaveiro
@en
Jose M.m. Caaveiro
@es
Jose M.m. Caaveiro
@nl
Jose M.m. Caaveiro
@sl
P1053
J-2790-2013
P106
P1153
57194713034
6602688045
P21
P31
P3829
P496
0000-0001-5568-2369