Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures. - Wikidata - wikimedia - TriplyDB

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures.

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures.

http://www.wikidata.org/entity/Q30660994

about

Mice with deficiency of G protein gamma3 are lean and have seizures Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration The pre-synaptic motor nerve terminal as a site for antibody-mediated neurotoxicity in autoimmune neuropathies and synaptopathies Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites The 'double lives' of membrane lipids. Workshop: Anno 2000. A lipid milestone Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C.Ganglioside GM3 is essential for the structural integrity and function of cochlear hair cells Physiopathological function of hematoside (GM3 ganglioside).Mice lacking ganglioside GM3 synthase exhibit complete hearing loss due to selective degeneration of the organ of Corti.The roles of glycosphingolipids in the proliferation and neural differentiation of mouse embryonic stem cells.Multiple phenotypic changes in mice after knockout of the B3gnt5 gene, encoding Lc3 synthase--a key enzyme in lacto-neolacto ganglioside synthesis Oligodendrocyte development and myelin biogenesis: parsing out the roles of glycosphingolipids Brain gangliosides in axon-myelin stability and axon regeneration.Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon-glial interactions Multi-system disorders of glycosphingolipid and ganglioside metabolism Production of multiple brain-like ganglioside species is dispensable for fas-induced apoptosis of lymphoid cells Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth.Sialylation is essential for early development in mice.Intracranial V. cholerae sialidase protects against excitotoxic neurodegeneration Ganglioside regulation of AMPA receptor trafficking.The organizing potential of sphingolipids in intracellular membrane transport.Simplifying complexity: genetically resculpting glycosphingolipid synthesis pathways in mice to reveal function.Fcγ receptor-mediated inflammation inhibits axon regeneration.A new assay for determining ganglioside sialyltransferase activities lactosylceramide-2,3-sialyltransferase (SAT I) and monosialylganglioside-2,3-sialyltransferase (SAT IV).Biosynthesis and degradation of mammalian glycosphingolipids.Glycosphingolipid functions: insights from engineered mouse models Endosomal/lysosomal processing of gangliosides affects neuronal cholesterol sequestration in Niemann-Pick disease type C.Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept.Ganglioside biochemistry Myelin-associated glycoprotein and complementary axonal ligands, gangliosides, mediate axon stability in the CNS and PNS: neuropathology and behavioral deficits in single- and double-null mice.Sialylation regulates brain structure and function.Membrane glycolipids in stem cells.The immunobiology of Guillain-Barré syndromes.Biosynthesis of the major brain gangliosides GD1a and GT1b Sphingolipids and membrane biology as determined from genetic models.Glycosignaling in neural stem cells: involvement of glycoconjugates in signal transduction modulating the neural stem cell fate.

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P2860

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures.

http://www.wikidata.org/entity/Q30660994

description

2000 nî lūn-bûn

@nan

2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2000年の論文

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2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures.

@ast

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures.

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type

label

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures.

@ast

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures.

@en

prefLabel

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures.

@ast

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures.

@en

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Journal of Biological Chemistry

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Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures

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P2093

Allende ML

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Bierfreund U

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Crawley JN

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Deng C

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Kawai H

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Kono M

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Sandhoff K

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Sango K

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Wada R

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Werth N

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6885-6888

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scholarly article

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10.1074/JBC.C000847200

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10

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276

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Tsuyoshi Miyakawa

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2000-12-27T00:00:00Z

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12194956

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