about
High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical librariesProtein-Directed Dynamic Combinatorial Chemistry: A Guide to Protein Ligand and Inhibitor DiscoveryDNA display of glycoconjugates to emulate oligomeric interactions of glycansIBC's 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences and the 2012 Annual Meeting of The Antibody Society: December 3-6, 2012, San Diego, CAWhat is a "DNA-Compatible" Reaction?Interaction-dependent PCR: identification of ligand-target pairs from libraries of ligands and libraries of targets in a single solution-phase experiment.Protein and small molecule microarrays: powerful tools for high-throughput proteomics.Identification of accessible human cancer biomarkers using ex vivo chemical proteomic strategies.Robust and systematic drug screening method using chemical arrays and the protein library: identification of novel inhibitors of carbonic anhydrase II.Translation of DNA into a library of 13,000 synthetic small-molecule macrocycles suitable for in vitro selection.In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitorsPhotoaffinity labeling of transcription factors by DNA-templated crosslinking.A sequential strand-displacement strategy enables efficient six-step DNA-templated synthesis.Small-molecule discovery from DNA-encoded chemical libraries.Microarray generation of thousand-member oligonucleotide libraries.20 years of DNA-encoded chemical libraries.Discovery of small-molecule interleukin-2 inhibitors from a DNA-encoded chemical library.Expanding the scope of PNA-encoded synthesis (PES): Mtt-protected PNA fully orthogonal to fmoc chemistry and a broad array of robust diversity-generating reactions.Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology.A DNA-templated synthesis of encoded small molecules by DNA self-assembly.Universal strategies for the DNA-encoding of libraries of small molecules using the chemical ligation of oligonucleotide tags.Methods for the creation of cyclic Peptide libraries for use in lead discovery.Identification of structure-activity relationships from screening a structurally compact DNA-encoded chemical library.Novel selection methods for DNA-encoded chemical librariesInterrogating target-specificity by parallel screening of a DNA-encoded chemical library against closely related proteins.Photon-regulated DNA-enzymatic nanostructures by molecular assembly.DNA-Encoded Dynamic Combinatorial Chemical Libraries.DNA as a versatile chemical component for catalysis, encoding, and stereocontrolDNA-Encoded Solid-Phase Synthesis: Encoding Language Design and Complex Oligomer Library SynthesisPhage-displayed macrocyclic glycopeptide libraries.Automated screening for small organic ligands using DNA-encoded chemical libraries.Optimized Reaction Conditions for Amide Bond Formation in DNA-Encoded Combinatorial LibrariesDNA-encoded chemical libraries: foundations and applications in lead discovery.Depletion and fractionation technologies in plasma proteomic analysis.Rarity gives a charm: evaluation of trace proteins in plasma and serum.Achievements, Challenges, and Opportunities in DNA-Encoded Library Research: An Academic Point of View.Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA-Encoded Chemical Library.Hit-Validation Methodologies for Ligands Isolated from DNA-Encoded Chemical Libraries.An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional ScreeningDiscovering Drugs with DNA-Encoded Library Technology: From Concept to Clinic with an Inhibitor of Soluble Epoxide Hydrolase.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Encoded self-assembling chemical libraries.
@ast
Encoded self-assembling chemical libraries.
@en
type
label
Encoded self-assembling chemical libraries.
@ast
Encoded self-assembling chemical libraries.
@en
prefLabel
Encoded self-assembling chemical libraries.
@ast
Encoded self-assembling chemical libraries.
@en
P2860
P356
P1433
P1476
Encoded self-assembling chemical libraries.
@en
P2093
Christoph E Dumelin
Samu Melkko
P2860
P2888
P304
P356
10.1038/NBT961
P577
2004-04-18T00:00:00Z