A hot spot of binding energy in a hormone-receptor interface
about
Epistructural Tension Promotes Protein AssociationsCharged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblastsp31comet blocks Mad2 activation through structural mimicryThe Fas-FADD death domain complex structure unravels signalling by receptor clusteringThe structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolutionThe RafC1 cysteine-rich domain contains multiple distinct regulatory epitopes which control Ras-dependent Raf activationInterleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayMolecular recognition of human angiogenin by placental ribonuclease inhibitor--an X-ray crystallographic study at 2.0 A resolution.Dehydron: a structurally encoded signal for protein interaction.Structure-based analysis of the herpes simplex virus glycoprotein D binding site present on herpesvirus entry mediator HveA (HVEM).CIITA leucine-rich repeats control nuclear localization, in vivo recruitment to the major histocompatibility complex (MHC) class II enhanceosome, and MHC class II gene transactivationDelineation of the peptide binding site of the human galanin receptorCrystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2AProtein-protein interactions in eukaryotic transcription initiation: structure of the preinitiation complexStructural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3 binding protein of human pyruvate dehydrogenase complexPCRPi-DB: a database of computationally annotated hot spots in protein interfacesStructural conservation of druggable hot spots in protein-protein interfacesTrp-26 imparts functional versatility to human alpha-defensin HNP1A structure-based benchmark for protein-protein binding affinityDruggability Assessment of Allosteric Proteins by Dynamics Simulations in the Presence of Probe MoleculesIntrinsically disordered proteins are potential drug targetsHot spots in prion protein for pathogenic conversionRapid mapping of protein functional epitopes by combinatorial alanine scanningFunctional and receptor binding characterization of recombinant murine macrophage inflammatory protein 2: sequence analysis and mutagenesis identify receptor binding epitopes.The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor bindingCrystal structure of human interleukin-10 at 1.6 A resolution and a model of a complex with its soluble receptorIn silico screening of mutational effects on enzyme-proteic inhibitor affinity: a docking-based approachELISA for Determination of Human Growth Hormone: Recognition of Helix 4 EpitopesVariation in structural location and amino acid conservation of functional sites in protein domain familiesSurfing the Protein-Protein Interaction Surface Using Docking Methods: Application to the Design of PPI InhibitorsInsights into cytokine-receptor interactions from cytokine engineeringFeatures of protein-protein interactions that translate into potent inhibitors: topology, surface area and affinitySynthetic peptide arrays for investigating protein interaction domainsStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewSmall-molecule inhibitors of the Myc oncoproteinAtomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition schemeThe structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding siteA ligand-reversible dimerization system for controlling protein-protein interactions
P2860
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P2860
A hot spot of binding energy in a hormone-receptor interface
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A hot spot of binding energy in a hormone-receptor interface
@ast
A hot spot of binding energy in a hormone-receptor interface
@en
type
label
A hot spot of binding energy in a hormone-receptor interface
@ast
A hot spot of binding energy in a hormone-receptor interface
@en
prefLabel
A hot spot of binding energy in a hormone-receptor interface
@ast
A hot spot of binding energy in a hormone-receptor interface
@en
P2860
P3181
P356
P1433
P1476
A hot spot of binding energy in a hormone-receptor interface
@en
P2093
P2860
P3181
P356
10.1126/SCIENCE.7529940
P407
P577
1995-01-20T00:00:00Z