Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.
about
The emerging role of oxylipins in thrombosis and diabetesβ-cell dedifferentiation in diabetes is important, but what is it?Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP)Mammalian lipoxygenases and their biological relevanceGlucose-6-phosphatase catalytic subunit gene familyFunctional and pathological roles of the 12- and 15-lipoxygenasesOxamate Improves Glycemic Control and Insulin Sensitivity via Inhibition of Tissue Lactate Production in db/db MicePPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunctionEnhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathwayRegulation of the insulin gene by glucose and fatty acidsGlucose-induced O₂ consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cellsEvidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats.12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western dietA feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis.Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection.UCP-2 and UCP-3 proteins are differentially regulated in pancreatic beta-cells.Protective unfolded protein response in human pancreatic beta cells transplanted into mice.Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male miceGene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes.Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult ratsPathological aspects of lipid peroxidation.12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets.Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes.High pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: inflammatory pathway inhibitionCathepsin inhibition-induced lysosomal dysfunction enhances pancreatic beta-cell apoptosis in high glucoseProtein profiling of mouse livers with peroxisome proliferator-activated receptor alpha activationEicosanoids, β-cell function, and diabetesGene-altered mice and metabolic flux control.Activation of Melatonin Signaling Promotes β-Cell Survival and FunctionExpression of PPARalpha modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout mice.Endoplasmic reticulum stress and insulin biosynthesis: a reviewBeta-cell mass plasticity in type 2 diabetes.Differential regulation of CHOP-10/GADD153 gene expression by MAPK signaling in pancreatic beta-cells.Islet β cell mass in diabetes and how it relates to function, birth, and death.Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell functionOverexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells.Uncoupling proteins: role in insulin resistance and insulin insufficiencyInteraction between cytokines and inflammatory cells in islet dysfunction, insulin resistance and vascular diseasep38 MAPK is a major regulator of MafA protein stability under oxidative stress.The glucose transporter 2 undergoes plasma membrane endocytosis and lysosomal degradation in a secretagogue-dependent manner.
P2860
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P2860
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.
@ast
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.
@en
type
label
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.
@ast
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.
@en
prefLabel
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.
@ast
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.
@en
P2093
P356
P1476
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.
@en
P2093
Arun Sharma
D Ross Laybutt
Dennis C Sgroi
Gordon C Weir
Justin Gaudet
P304
10912-10921
P356
10.1074/JBC.M111751200
P407
P577
2002-01-08T00:00:00Z