p38 MAPK is a major regulator of MafA protein stability under oxidative stress. - Wikidata - wikimedia - TriplyDB

p38 MAPK is a major regulator of MafA protein stability under oxidative stress.

p38 MAPK is a major regulator of MafA protein stability under oxidative stress.

http://www.wikidata.org/entity/Q37283631

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β-cell dedifferentiation in diabetes is important, but what is it?Differentiation of pancreatic endocrine progenitors reversibly blocked by premature induction of MafA Heterozygous SOD2 deletion impairs glucose-stimulated insulin secretion, but not insulin action, in high-fat-fed mice.Regulation of the CCL2 gene in pancreatic β-cells by IL-1β and glucocorticoids: role of MKP-1.Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.Mice lacking the p43 mitochondrial T3 receptor become glucose intolerant and insulin resistant during aging.Aldosterone induces clonal β-cell failure through glucocorticoid receptor.Islet β cell mass in diabetes and how it relates to function, birth, and death.Thyroid hormone promotes postnatal rat pancreatic β-cell development and glucose-responsive insulin secretion through MAFA.Preventing p38 MAPK-mediated MafA degradation ameliorates β-cell dysfunction under oxidative stress.Inactivation of specific β cell transcription factors in type 2 diabetes.The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus.MafA and MafB activity in pancreatic β cells.Proper activation of MafA is required for optimal differentiation and maturation of pancreatic β-cells Shielding Engineered Islets With Mesenchymal Stem Cells Enhance Survival Under Hypoxia.The undoing and redoing of the diabetic β-cell.Distinct Shift in Beta-Cell Glutaredoxin 5 Expression Is Mediated by Hypoxia and Lipotoxicity Both In Vivo and In Vitro.MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma.Reversal of angiotensin ll-induced β-cell dedifferentiation via inhibition of NF-κb signaling

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p38 MAPK is a major regulator of MafA protein stability under oxidative stress.

http://www.wikidata.org/entity/Q37283631

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 30 April 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

p38 MAPK is a major regulator of MafA protein stability under oxidative stress.

@en

p38 MAPK is a major regulator of MafA protein stability under oxidative stress.

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type

label

p38 MAPK is a major regulator of MafA protein stability under oxidative stress.

@en

p38 MAPK is a major regulator of MafA protein stability under oxidative stress.

@nl

prefLabel

p38 MAPK is a major regulator of MafA protein stability under oxidative stress.

@en

p38 MAPK is a major regulator of MafA protein stability under oxidative stress.

@nl

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Molecular Endocrinology

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p38 MAPK is a major regulator of MafA protein stability under oxidative stress.

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Arun Sharma

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D Ross Laybutt

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George King

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Gordon Weir

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Ilham El Khattabi

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Pedro Geraldes

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Samit Shah

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Takuma Kondo

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P2860

MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene

MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation

Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.

Phosphorylation of MafA is essential for its transcriptional and biological properties

Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells

GSK-3-mediated phosphorylation enhances Maf-transforming activity

Regulation of mouse lens fiber cell development and differentiation by the Maf gene

Regulation of lens fiber cell differentiation by transcription factor c-Maf

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

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1281-1290

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scholarly article

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10.1210/ME.2008-0482

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8

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23

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Susan Bonner-Weir

Wataru Nishimura

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2009-04-30T00:00:00Z

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19407223

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2718751

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