Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility.
about
Paracrine mechanisms involved in the control of early stages of Mammalian spermatogenesisGrowth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switchRole for the adaptor protein Grb10 in the activation of AktMale infertility, impaired spermatogenesis, and azoospermia in mice deficient for the pseudophosphatase Sbf1Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell developmentPlasticity of male germline stem cells and their applications in reproductive and regenerative medicineStructural and functional properties of platelet-derived growth factor and stem cell factor receptorsAdvantages of using the CRISPR/Cas9 system of genome editing to investigate male reproductive mechanisms using mouse modelsControl of Oocyte Reawakening by Kit.Telomerase activity and telomere length in male germ cellsGab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-KitRole of c-kit in mammalian spermatogenesisThe regulation of epidermal melanogenesis via cAMP and/or PKC signaling pathways: insights for the development of hypopigmenting agentsGrowth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 geneEssential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in miceDeficiency in the multicopy Sycp3-like X-linked genes Slx and Slxl1 causes major defects in spermatid differentiationTargeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineagesTissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesisNovel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli CellsIdentification of a novel point mutation of mouse proto-oncogene c-kit through N-ethyl-N-nitrosourea mutagenesisDissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transferThe Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertilityKIT is required for hepatic function during mouse post-natal development.Microgravity promotes differentiation and meiotic entry of postnatal mouse male germ cells.Kit ligand cytoplasmic domain is essential for basolateral sorting in vivo and has roles in spermatogenesis and hematopoiesisEssential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.Gdnf upregulates c-Fos transcription via the Ras/Erk1/2 pathway to promote mouse spermatogonial stem cell proliferation.C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferationc-Kit-mediated functional positioning of stem cells to their niches is essential for maintenance and regeneration of adult hematopoiesis.Mutations in the c-Kit gene disrupt mitogen-activated protein kinase signaling during tumor development in adenoid cystic carcinoma of the salivary glandsTr-kit-induced resumption of the cell cycle in mouse eggs requires activation of a Src-like kinase.An allelic series of mutations in the Kit ligand gene of mice. II. Effects of ethylnitrosourea-induced Kitl point mutations on survival and peripheral blood cells of Kitl(Steel) miceLocal signalling environments and human male infertility: what we can learn from mouse models.Oocyte-granulosa cell interactions during mouse follicular development: regulation of kit ligand expression and its role in oocyte growthRetinoic acid regulates Kit translation during spermatogonial differentiation in the mouseRanBPM is essential for mouse spermatogenesis and oogenesis.Molecular mechanisms utilized by alternative c-kit gene products in the control of spermatogonial proliferation and sperm-mediated egg activation.KIT mutations are common in testicular seminomas.The role of retinoblastoma protein family in the control of germ cell proliferation, differentiation and survival.
P2860
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P2860
Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility.
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Kit/stem cell factor receptor- ...... essential for male fertility.
@ast
Kit/stem cell factor receptor- ...... essential for male fertility.
@en
type
label
Kit/stem cell factor receptor- ...... essential for male fertility.
@ast
Kit/stem cell factor receptor- ...... essential for male fertility.
@en
prefLabel
Kit/stem cell factor receptor- ...... essential for male fertility.
@ast
Kit/stem cell factor receptor- ...... essential for male fertility.
@en
P2093
P2860
P356
P1433
P1476
Kit/stem cell factor receptor- ...... essential for male fertility.
@en
P2093
P2860
P2888
P304
P356
10.1038/72814
P407
P577
2000-02-01T00:00:00Z