Nimbolide targets BCL2 and induces apoptosis in preclinical models of Waldenströms macroglobulinemia.
about
Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its developmentMechanisms of ibrutinib resistance in chronic lymphocytic leukaemia and non-Hodgkin lymphoma.Waldenstrom macroglobulinemia cells devoid of BTKC481S or CXCR4WHIM-like mutations acquire resistance to ibrutinib through upregulation of Bcl-2 and AKT resulting in vulnerability towards venetoclax or MK2206 treatment.Coinhibition of the deubiquitinating enzymes, USP14 and UCHL5, with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cellsNimbolide induces apoptosis in human nasopharyngeal cancer cells.DnaJ homolog subfamily A member1 (DnaJ1) is a newly discovered anti-apoptotic protein regulated by azadirachtin in Sf9 cells.
P2860
Nimbolide targets BCL2 and induces apoptosis in preclinical models of Waldenströms macroglobulinemia.
description
2014 nî lūn-bûn
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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Nimbolide targets BCL2 and ind ...... aldenströms macroglobulinemia.
@ast
Nimbolide targets BCL2 and ind ...... aldenströms macroglobulinemia.
@en
type
label
Nimbolide targets BCL2 and ind ...... aldenströms macroglobulinemia.
@ast
Nimbolide targets BCL2 and ind ...... aldenströms macroglobulinemia.
@en
prefLabel
Nimbolide targets BCL2 and ind ...... aldenströms macroglobulinemia.
@ast
Nimbolide targets BCL2 and ind ...... aldenströms macroglobulinemia.
@en
P2093
P2860
P356
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P1476
Nimbolide targets BCL2 and ind ...... aldenströms macroglobulinemia.
@en
P2093
A Chanan-Khan
M G Heckman
M-K K Blake
S Ailawadhi
T R Caulfield
P2860
P2888
P356
10.1038/BCJ.2014.74
P577
2014-11-07T00:00:00Z
P5875
P6179
1017482913