A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening.
about
Novel Natural Product- and Privileged Scaffold-Based Tubulin Inhibitors Targeting the Colchicine Binding SiteProtein and small molecule microarrays: powerful tools for high-throughput proteomics.Phenotypic analysis of images of zebrafish treated with Alzheimer's gamma-secretase inhibitors.A chemical screen identifies novel compounds that overcome glial-mediated inhibition of neuronal regeneration.Nanomolar-Potency Aminophenyl-1,3,5-triazine Activators of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channel for Prosecretory Therapy of Dry Eye Diseases.Combinatorial synthesis of galactosyl-1,3,5-triazines as novel nucleoside analogues.Diversity-driven chemical probe development for biomolecules: beyond hypothesis-driven approach.15 years of zebrafish chemical screeningIdentification of 12Cysbeta on tubulin as the binding site of tubulyzine.Synthesis and biological evaluation of imidazopyridine-oxindole conjugates as microtubule-targeting agents.The zebrafish embryo as a tool for screening and characterizing pleurocidin host-defense peptides as anti-cancer agents.Diversity-oriented approach for chemical biology.Chemical screening in zebrafish for novel biological and therapeutic discovery.Pharmacology and toxicology of pahayokolide A, a bioactive metabolite from a freshwater species of Lyngbya isolated from the Florida EvergladesUse of non-mammalian alternative models for neurotoxicological studyAdvances in zebrafish chemical screening technologies.Use of zebrafish embryos for small molecule screening related to cancer.Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish.Pyrazole-oxadiazole conjugates: synthesis, antiproliferative activity and inhibition of tubulin polymerization.A countermeasure development pipeline.Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression.Dendrimers terminated with dichlorotriazine groups provide a route to compositional diversity.A high-throughput analysis method to detect regions of interest and quantify zebrafish embryo images.Solid-phase Synthesis of Combinatorial 2,4-Disubstituted-1,3,5-Triazine via Amine Nucleophilic Reaction
P2860
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P2860
A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening.
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A novel microtubule destabiliz ...... nd zebrafish embryo screening.
@ast
A novel microtubule destabiliz ...... nd zebrafish embryo screening.
@en
type
label
A novel microtubule destabiliz ...... nd zebrafish embryo screening.
@ast
A novel microtubule destabiliz ...... nd zebrafish embryo screening.
@en
prefLabel
A novel microtubule destabiliz ...... nd zebrafish embryo screening.
@ast
A novel microtubule destabiliz ...... nd zebrafish embryo screening.
@en
P2093
P356
P1476
A novel microtubule destabiliz ...... nd zebrafish embryo screening.
@en
P2093
Alexander F Schier
Daniel P Walsh
Eric M Jacobson
Gustavo R Rosania
Ho-Sang Moon
Jae Wook Lee
Jennifer C Lam
Michael R Luzung
Puja B Parikh
Sonya M Khersonsky
P304
11608-11609
P356
10.1021/JA026720I
P407
P577
2002-10-01T00:00:00Z