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Neural stem cell specific fluorescent chemical probe binding to FABP7Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. fusion [corrected] inhibitionIn vivo detection of macrophage recruitment in hind-limb ischemia using a targeted near-infrared fluorophoreSynthesis and anticancer activity studies of cyclopamine derivativesIdentification of fluorescent compounds with non-specific binding property via high throughput live cell microscopyStyryl-based and tricyclic compounds as potential anti-prion agentsA highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutaseOptical visualisation of thermogenesis in stimulated single-cell brown adipocytes.A molecular fluorescent probe for targeted visualization of temperature at the endoplasmic reticulumMake caffeine visible: a fluorescent caffeine "traffic light" detector.Nitrophenol resins for facile amide and sulfonamide library synthesis.Combinatorial synthesis of benzimidazolium dyes and its diversity directed application toward GTP-selective fluorescent chemosensors.Divergent syntheses of all stereoisomers of phytosphingosine and their use in the construction of a ceramide library.A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening.Novel orthogonal strategy toward solid-phase synthesis of 1,3,5-substituted triazines.Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2.Combinatorial synthesis of a triphenylmethine library and their application in the development of surface enhanced Raman scattering (SERS) probes.Solid phase combinatorial synthesis of a xanthone library using click chemistry and its application to an embryonic stem cell probe.Chemoinformatic analysis of a supertargeted combinatorial library of styryl molecules.Tubulyzine, a novel tri-substituted triazine, prevents the early cell death of transplanted myogenic cells and improves transplantation success.The synthesis and biological characterization of a ceramide library.Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening.Tagged library approach to chemical genomics and proteomics.Identification of a novel protein regulating microtubule stability through a chemical approach.Molecular evolution using intramolecular acyl migration on myo-inositol benzoates with thermodynamic and kinetic selectors.Identification of compounds that bind mitochondrial F1F0 ATPase by screening a triazine library for correction of albinism.Microarrays of tagged combinatorial triazine libraries in the discovery of small-molecule ligands of human IgG.Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells.Dissection of melanogenesis with small molecules identifies prohibitin as a regulator.Identification of a new class of prostaglandin transporter inhibitors and characterization of their biological effects on prostaglandin E2 transport.Triazine-based tyrosinase inhibitors identified by chemical genetic screening.RNA-selective, live cell imaging probes for studying nuclear structure and function.Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish.Forward chemical genetic approach identifies new role for GAPDH in insulin signaling.A high-throughput screen for compounds that inhibit aggregation of the Alzheimer's peptide.Combinatorial rosamine library and application to in vivo glutathione probe.A protocol for preparing, characterizing and using three RNA-specific, live cell imaging probes: E36, E144 and F22.Tagged library approach facilitates forward chemical genetics.Rapid identification of immunostimulatory alpha-galactosylceramides using synthetic combinatorial libraries.Combinatorial dapoxyl dye library and its application to site selective probe for human serum albumin.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Young-Tae Chang
@ast
Young-Tae Chang
@en
Young-Tae Chang
@es
Young-Tae Chang
@nl
Young-Tae Chang
@sl
type
label
Young-Tae Chang
@ast
Young-Tae Chang
@en
Young-Tae Chang
@es
Young-Tae Chang
@nl
Young-Tae Chang
@sl
prefLabel
Young-Tae Chang
@ast
Young-Tae Chang
@en
Young-Tae Chang
@es
Young-Tae Chang
@nl
Young-Tae Chang
@sl
P108
P1053
B-2780-2010
P106
P108
P21
P31
P3829
P496
0000-0002-1927-3688
P569
2000-01-01T00:00:00Z