Stepwise manipulation of DNA specificity in Flp recombinase: progressively adapting Flp to individual and combinatorial mutations in its target site.
about
A combinatorial approach to create artificial homing endonucleases cleaving chosen sequencesAn ultrasensitive site-specific DNA recombination assay based on dual-color fluorescence cross-correlation spectroscopy.Expanding the scope of site-specific recombinases for genetic and metabolic engineeringA specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and waterMultiple new site-specific recombinases for use in manipulating animal genomesConditional and inducible gene recombineering in the mouse inner earLaboratory-directed protein evolutionIdentification of key structural determinants of the IntI1 integron integrase that influence attC x attI1 recombination efficiency.Directed evolution of recombinase specificity by split gene reassemblyThe partitioning and copy number control systems of the selfish yeast plasmid: an optimized molecular design for stable persistence in host cells.Efficient design of meganucleases using a machine learning approach.Versatile genetic paintbrushes: Brainbow technologies.Engineering selection stringency on expression vector for the production of recombinant human alpha1-antitrypsin using Chinese Hamster ovary cells.Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy.Vika/vox, a novel efficient and specific Cre/loxP-like site-specific recombination system.Genome engineering: Drosophila melanogaster and beyondAdvances in Mammalian cell line development technologies for recombinant protein production.Targeted approaches for gene therapy and the emergence of engineered meganucleases.Utilization of Site-Specific Recombination in Biopharmaceutical Production.Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites.Binding and catalytic contributions to site recognition by flp recombinase.A genome-wide analysis of FRT-like sequences in the human genome.Recombinase-Mediated Cassette Exchange Using Adenoviral Vectors.Target-specific variants of Flp recombinase mediate genome engineering reactions in mammalian cells.Engineering selection stringency on expression vector for the production of recombinant human alpha1-antitrypsin using Chinese Hamster Ovary cells.Flybow: genetic multicolor cell labeling for neural circuit analysis in Drosophila melanogaster.Engineering altered protein-DNA recognition specificity.
P2860
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P2860
Stepwise manipulation of DNA specificity in Flp recombinase: progressively adapting Flp to individual and combinatorial mutations in its target site.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Stepwise manipulation of DNA s ...... mutations in its target site.
@ast
Stepwise manipulation of DNA s ...... mutations in its target site.
@en
type
label
Stepwise manipulation of DNA s ...... mutations in its target site.
@ast
Stepwise manipulation of DNA s ...... mutations in its target site.
@en
prefLabel
Stepwise manipulation of DNA s ...... mutations in its target site.
@ast
Stepwise manipulation of DNA s ...... mutations in its target site.
@en
P2093
P1476
Stepwise manipulation of DNA s ...... mutations in its target site.
@en
P2093
A Francis Stewart
Jay H Konieczka
Makkuni Jayaram
Yuri Voziyanov
P356
10.1016/S0022-2836(02)01364-5
P407
P577
2003-02-01T00:00:00Z