Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis.
about
A non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and functionNovel Molecular Markers for Breast CancerAberrant Splicing of Estrogen Receptor, HER2, and CD44 Genes in Breast CancerMMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancerG1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target PtprvThe Arf-inducing transcription factor Dmp1 encodes a transcriptional activator of amphiregulin, thrombospondin-1, JunB and Egr1A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation.Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor.Haploinsufficient tumor suppressor genes.Classical and Novel Prognostic Markers for Breast Cancer and their Clinical Significance.Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages.Nucleolar adaptation in human cancerThe molecular scaffold kinase suppressor of Ras 1 is a modifier of RasV12-induced and replicative senescenceCritical roles of DMP1 in human epidermal growth factor receptor 2/neu-Arf-p53 signaling and breast cancer development.Arf tumor suppressor promoter monitors latent oncogenic signals in vivoEarly growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescenceDmp1α inhibits HER2/neu-induced mammary tumorigenesis.Signal transduction involving the dmp1 transcription factor and its alteration in human cancerDMP1β, a splice isoform of the tumour suppressor DMP1 locus, induces proliferation and progression of breast cancerComparative pathogenesis of epsilonretroviruses.What has senescence got to do with cancer?Regulation of murine hematopoietic stem cell quiescence by Dmtf1Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint.Dmp1 and tumor suppression.Expression of Dmp1 in specific differentiated, nonproliferating cells and its regulation by E2FsHuman DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation.MdmX promotes bipolar mitosis to suppress transformation and tumorigenesis in p53-deficient cells and mice.Emerging roles of DMP1 in lung cancerPrognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.Role of DMP1 and its future in lung cancer diagnostics.Cooperation between Dmp1 loss and cyclin D1 overexpression in breast cancer.Oncogene-induced senescence: an essential role for Runx.Aberrant splicing of the DMP1-ARF-MDM2-p53 pathway in cancerAberrant expression of cyclin D1 in cancer.Clinical applications of mouse models for breast cancer engaging HER2/neu.Is PML a Tumor Suppressor?Transcription factors that interact with p53 and Mdm2Oncogenic and tumor-suppressive mouse models for breast cancer engaging HER2/neu.Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer.Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas
P2860
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P2860
Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Disruption of the ARF transcri ...... sformation, and tumorigenesis.
@ast
Disruption of the ARF transcri ...... sformation, and tumorigenesis.
@en
type
label
Disruption of the ARF transcri ...... sformation, and tumorigenesis.
@ast
Disruption of the ARF transcri ...... sformation, and tumorigenesis.
@en
prefLabel
Disruption of the ARF transcri ...... sformation, and tumorigenesis.
@ast
Disruption of the ARF transcri ...... sformation, and tumorigenesis.
@en
P2093
P2860
P1433
P1476
Disruption of the ARF transcri ...... sformation, and tumorigenesis.
@en
P2093
J L Cleveland
M F Roussel
P2860
P304
P577
2000-07-01T00:00:00Z