Effects of buffering conditions and culture pH on production rates and glycosylation of clinical phase I anti-melanoma mouse IgG3 monoclonal antibody R24.
about
Kinetic simulation of a centrifugal bioreactor for high population density hybridoma culturePro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid.Modifications of therapeutic proteins: challenges and prospects.scFv-based "Grababody" as a general strategy to improve recruitment of immune effector cells to antibody-targeted tumors.A novel method for monitoring monoclonal antibody production during cell culture.Glycosylation: impact, control and improvement during therapeutic protein production.A comparison of orbitally-shaken and stirred-tank bioreactors: pH modulation and bioreactor type affect CHO cell growth and protein glycosylation.Glycosylation of monoclonal antibody products: Current status and future prospects.Insights into pH-induced metabolic switch by flux balance analysis.Impact of cell culture on recombinant monoclonal antibody product heterogeneity.Mechanism for multiplicity of steady states with distinct cell concentration in continuous culture of mammalian cells.Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation.Effects of glutamine and asparagine on recombinant antibody production using CHO-GS cell lines.CHO cell line specific prediction and control of recombinant monoclonal antibody N-glycosylation.Effect of culture pH on recombinant antibody production by a new human cell line, F2N78, grown in suspension at 33.0 °C and 37.0 °C.Modulation of antibody galactosylation through feeding of uridine, manganese chloride, and galactose.Comparisons of optical pH and dissolved oxygen sensors with traditional electrochemical probes during mammalian cell culture.Fermentanomics informed amino acid supplementation of an antibody producing mammalian cell culture.Mannose metabolism in recombinant CHO cells and its effect on IgG glycosylation.Characterization of the influence of cultivation parameters on extracellular modifications of antibodies during fermentation.Cell culture media supplementation of uncommonly used sugars sucrose and tagatose for the targeted shifting of protein glycosylation profiles of recombinant protein therapeutics.Cell culture media supplementation of infrequently used sugars for the targeted shifting of protein glycosylation profiles.Identifying a robust design space for glycosylation during monoclonal antibody production.Engineer Medium and Feed for Modulating N-Glycosylation of Recombinant Protein Production in CHO Cell Culture.
P2860
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P2860
Effects of buffering conditions and culture pH on production rates and glycosylation of clinical phase I anti-melanoma mouse IgG3 monoclonal antibody R24.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Effects of buffering condition ...... IgG3 monoclonal antibody R24.
@ast
Effects of buffering condition ...... IgG3 monoclonal antibody R24.
@en
type
label
Effects of buffering condition ...... IgG3 monoclonal antibody R24.
@ast
Effects of buffering condition ...... IgG3 monoclonal antibody R24.
@en
prefLabel
Effects of buffering condition ...... IgG3 monoclonal antibody R24.
@ast
Effects of buffering condition ...... IgG3 monoclonal antibody R24.
@en
P2093
P2860
P356
P1476
Effects of buffering condition ...... IgG3 monoclonal antibody R24.
@en
P2093
Dijana Sagi
Harald S Conradt
Manfred Nimtz
Sven E Kemminer
P2860
P304
P356
10.1002/BIT.10673
P577
2003-08-01T00:00:00Z