PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of mice
about
Hyperthermia induces the ER stress pathway.PERK (EIF2AK3) regulates proinsulin trafficking and quality control in the secretory pathway.Endoplasmic reticulum stress and cancer.The cell biology of the unfolded protein response.miR-211 suppresses epithelial ovarian cancer proliferation and cell-cycle progression by targeting Cyclin D1 and CDK6.Perk gene dosage regulates glucose homeostasis by modulating pancreatic β-cell functions.Signaling through alternative Integrated Stress Response pathways compensates for GCN2 loss in a mouse model of soft tissue sarcomaCell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapymiR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner.Type I interferons mediate pancreatic toxicities of PERK inhibition.ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth.PERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Premalignant Granule Cell Precursor Apoptosis.NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2α-ATF4 signalling in breast cancer.The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapiesPERK in beta cell biology and insulin biogenesis.Endoplasmic reticulum stress, pancreatic β-cell degeneration, and diabetes.Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integrationEndoplasmic reticulum stress and angiogenesis: is there an interaction between them?The role of endoplasmic reticulum stress in human pathology.The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation.The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones.Role of the unfolded protein response in organ physiology: lessons from mouse models.New Hope for Pancreatic Ductal Adenocarcinoma Treatment Targeting Endoplasmic Reticulum Stress Response: A Systematic Review
P2860
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P2860
PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of mice
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
PERK regulates the proliferati ...... the endocrine pancreas of mice
@ast
PERK regulates the proliferati ...... the endocrine pancreas of mice
@en
type
label
PERK regulates the proliferati ...... the endocrine pancreas of mice
@ast
PERK regulates the proliferati ...... the endocrine pancreas of mice
@en
prefLabel
PERK regulates the proliferati ...... the endocrine pancreas of mice
@ast
PERK regulates the proliferati ...... the endocrine pancreas of mice
@en
P2093
P2860
P1433
P1476
PERK regulates the proliferati ...... the endocrine pancreas of mice
@en
P2093
Barbara McGrath
Douglas R Cavener
Sounak Gupta
P2860
P356
10.1371/JOURNAL.PONE.0008008
P407
P577
2009-11-24T00:00:00Z