The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones.

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The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones.

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http://www.wikidata.org/entity/Q52695056

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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The protein kinase PERK/EIF2AK ...... oplasmic reticulum chaperones.

@en

The protein kinase PERK/EIF2AK ...... oplasmic reticulum chaperones.

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Item

label

The protein kinase PERK/EIF2AK ...... oplasmic reticulum chaperones.

@en

The protein kinase PERK/EIF2AK ...... oplasmic reticulum chaperones.

@nl

prefLabel

The protein kinase PERK/EIF2AK ...... oplasmic reticulum chaperones.

@en

The protein kinase PERK/EIF2AK ...... oplasmic reticulum chaperones.

@nl

P1476

The protein kinase PERK/EIF2AK ...... doplasmic reticulum chaperones

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P2093

Adrienne W Paton

http://www.w3.org/2001/XMLSchema#string

Barbara C McGrath

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Carrie R Sowers

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James C Paton

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Jingjie Hu

http://www.w3.org/2001/XMLSchema#string

Rebecca A Bourne

http://www.w3.org/2001/XMLSchema#string

Rong Wang

http://www.w3.org/2001/XMLSchema#string

Sarah C Bevilacqua

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P2860

Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3

Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment

Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (P

EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

ER chaperones in mammalian development and human diseases

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells

An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

P304

5134-5149

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scholarly article

P356

10.1074/JBC.M117.813790

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P407

English

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P478

293

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P50

Sophie Collardeau-Frachon

Douglas R Cavener

Marc Nicolino

P577

2018-02-14T00:00:00Z

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P698

29444822

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P921

molecular chaperones

endoplasmic reticulum

P932

5892574

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