Protein Ensembles: How Does Nature Harness Thermodynamic Fluctuations for Life? The Diverse Functional Roles of Conformational Ensembles in the Cell.
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The contribution of intrinsically disordered regions to protein function, cellular complexity, and human diseasePredicting Protein Dynamics and Allostery Using Multi-Protein Atomic Distance Constraints.Preferential binding effects on protein structure and dynamics revealed by coarse-grained Monte Carlo simulation.Visualizing single-stranded nucleic acids in solution.Release of Cytochrome C from Bax Pores at the Mitochondrial Membrane.Induced Fit in Protein Multimerization: The HFBI Case.Rosetta:MSF: a modular framework for multi-state computational protein design.Metadynamic metainference: Convergence towards force field independent structural ensembles of a disordered peptide.Exploiting computationally derived out-of-the-box protein conformations for drug design.The principle of conformational signaling.Conformational selection in amyloid-based immunotherapy: Survey of crystal structures of antibody-amyloid complexes.Applications of NMR and computational methodologies to study protein dynamics.Intrinsic protein disorder in oncogenic KRAS signaling.Conformational dynamics of cancer-associated MyD88-TIR domain mutant L252P (L265P) allosterically tilts the landscape toward homo-dimerization.Enhanced unbiased sampling of protein dynamics using evolutionary coupling information.Entropy redistribution controls allostery in a metalloregulatory protein.Frustration, function and folding.Controlled self-sorting in self-assembled cage complexes.Pockets as structural descriptors of EGFR kinase conformations.Local and global anatomy of antibody-protein antigen recognition.Rational design of proteins that exchange on functional timescales.Deciphering Conformational Changes Associated with the Maturation of Thrombin Anion Binding Exosite I.Binding of protofibrillar Aβ trimers to lipid bilayer surface enhances Aβ structural stability and causes membrane thinning.Allosteric control of antibody-prion recognition through oxidation of a disulfide bond between the CH and CL chains.Protein dynamics: Conformational footprints.Maintaining and Enhancing Diversity of Sampled Protein Conformations in Robotics-Inspired Methods.Homology modeling in a dynamical world.Expediting dynamics approach to understand the influence of 14-3-3ζ causing metastatic cancer through the interaction of YAP1 and β-TRCP.Understanding the connection between conformational changes of peptides and equilibrium thermal fluctuations.Guest-Induced Folding and Self-Assembly of Conformationally Adaptive Macrocycles into Nanosheets and Nanotubes.Effects of side chains of oxatub[4]arene on its conformational interconversion, molecular recognition and macroscopic self-assembly.Elevated μs-ms timescale backbone dynamics in the transition state analog form of arginine kinase.Unexpectedly Enhanced Solubility of Aromatic Amino Acids and Peptides in an Aqueous Solution of Divalent Transition-Metal Cations.Conformational selection underpins recognition of multiple DNA sequences by proteins and consequent functional actions.Oxatub[5,6]arene: synthesis, conformational analysis, and the recognition of C60 and C70.Modeling the effects of lattice defects on microtubule breaking and healing.Activation and desensitization of ionotropic glutamate receptors by selectively triggering pre-existing motions.CalFitter: a web server for analysis of protein thermal denaturation data.Inhibition of the precursor and mature forms of HIV-1 protease as a tool for drug evaluation.Protein design: from computer models to artificial intelligence
P2860
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P2860
Protein Ensembles: How Does Nature Harness Thermodynamic Fluctuations for Life? The Diverse Functional Roles of Conformational Ensembles in the Cell.
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Protein Ensembles: How Does Na ...... ational Ensembles in the Cell.
@ast
Protein Ensembles: How Does Na ...... ational Ensembles in the Cell.
@en
type
label
Protein Ensembles: How Does Na ...... ational Ensembles in the Cell.
@ast
Protein Ensembles: How Does Na ...... ational Ensembles in the Cell.
@en
prefLabel
Protein Ensembles: How Does Na ...... ational Ensembles in the Cell.
@ast
Protein Ensembles: How Does Na ...... ational Ensembles in the Cell.
@en
P2093
P1433
P1476
Protein Ensembles: How Does Na ...... ational Ensembles in the Cell.
@en
P2093
Guanghong Wei
P304
P356
10.1021/ACS.CHEMREV.5B00562
P577
2016-01-25T00:00:00Z