Cloning and characterization of two human Ro52-specific monoclonal autoantibodies directed towards a domain associated with congenital heart block.
about
Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block.Remission of congenital complete heart block without anti-Ro/La antibodies: A case reportPathogenicity and proteomic signatures of autoantibodies to Ro and La.Ro52, Ro60 and La IgG autoantibody levels and Ro52 IgG subclass profiles longitudinally throughout pregnancy in congenital heart block risk pregnancies.Structurally derived mutations define congenital heart block-related epitopes within the 200-239 amino acid stretch of the Ro52 protein.Identification of discrete epitopes of Ro52p200 and association with fetal cardiac conduction system manifestations in a rodent model.
P2860
Q28257418-FA71E49F-2AD7-4721-A0F5-00AC5F252F59Q36402505-25C0E112-2B13-4B45-AE93-901FB8661437Q37643023-50BAA78C-376B-4743-90F6-B6EB803EBFFCQ37976260-8C8B2BE3-64F1-4797-BAAA-4EF624610D83Q43421348-711198E1-DB4F-4C72-AF9F-08D302789FD2Q45245825-78CCD70B-6FEB-4472-8790-FEAA81494C62Q51557775-052CE875-1B5F-41D7-8AE5-C4C1A2186795
P2860
Cloning and characterization of two human Ro52-specific monoclonal autoantibodies directed towards a domain associated with congenital heart block.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Cloning and characterization o ...... d with congenital heart block.
@ast
Cloning and characterization o ...... d with congenital heart block.
@en
type
label
Cloning and characterization o ...... d with congenital heart block.
@ast
Cloning and characterization o ...... d with congenital heart block.
@en
prefLabel
Cloning and characterization o ...... d with congenital heart block.
@ast
Cloning and characterization o ...... d with congenital heart block.
@en
P2093
P1476
Cloning and characterization o ...... d with congenital heart block.
@en
P2093
Danielle Hof
Hanna Brauner
Lars Ottosson
Maria Sunnerhagen
Pär Säfsten
Stina Salomonsson
P304
P356
10.1016/J.JAUT.2003.11.004
P577
2004-03-01T00:00:00Z