about
Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humansEvolution of JAK-STAT pathway components: mechanisms and role in immune system developmentLPS induces the interaction of a transcription factor, LPS-induced TNF-alpha factor, and STAT6(B) with effects on multiple cytokinesLeukemia and benzeneCrystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound stateLPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathwaysMultifaceted intervention by the Hsp90 inhibitor ganetespib (STA-9090) in cancer cells with activated JAK/STAT signalingIdentification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation.Statins suppress interleukin-6-induced monocyte chemo-attractant protein-1 by inhibiting Janus kinase/signal transducers and activators of transcription pathways in human vascular endothelial cells.Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation via upregulation of STAT3A Non-ATP-Competitive Dual Inhibitor of JAK2 and BCR-ABL Kinases: Elucidation of a Novel Therapeutic Spectrum Based on Substrate Competitive Inhibition.Dasatinib impairs long-term expansion of leukemic progenitors in a subset of acute myeloid leukemia cases.Erythropoietin receptor signaling is membrane raft dependent.An endoplasmic reticulum stress-initiated sphingolipid metabolite, ceramide-1-phosphate, regulates epithelial innate immunity by stimulating β-defensin productionInterleukin-12 p40- and Fas ligand-dependent apoptotic pathways involving STAT-1 phosphorylation are triggered during infection with a virulent strain of Toxoplasma gondiip27Kip1 and p130 cooperate to regulate hematopoietic cell proliferation in vivo.Hematopoietic stem cells and hematopoiesis.Inflammation regulates TMPRSS6 expression via STAT5.Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells.Interleukin-6/soluble interleukin-6 receptor signaling attenuates proliferation and invasion, and induces morphological changes of a newly established pleomorphic malignant fibrous histiocytoma cell line.Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies.Hck is a key regulator of gene expression in alternatively activated human monocytesPromiscuous and lineage-specific roles of cell cycle regulators in haematopoiesisMolecular therapeutic approaches to acute myeloid leukemia: targeting aberrant chromatin dynamics and signal transduction.Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor.STAT5 acts as a repressor to regulate early embryonic erythropoiesis.Activation of the Jak3 pathway and myeloid differentiation.Constitutive Activation of Interleukin-13/STAT6 Contributes to Kaposi's Sarcoma-Associated Herpesvirus-Related Primary Effusion Lymphoma Cell Proliferation and Survival.Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer.CD318/CUB-domain-containing protein 1 expression on cord blood hematopoietic progenitors.Nilotinib treatment in mouse models of P190 Bcr/Abl lymphoblastic leukemia.Cytokines in the differentiation therapy of leukemia: from laboratory investigations to clinical applications.Cross-regulation of JAK and Src kinases.Phosphoproteomics and lung cancer research.The role of Janus kinases in haemopoiesis and haematological malignancy.LRG-accelerated differentiation defines unique G-CSFR signaling pathways downstream of PU.1 and C/EBPepsilon that modulate neutrophil activationSignal transduction pathways that contribute to myeloid differentiation.sIL-6R: more than an agonist?Roles for deregulated receptor tyrosine kinases and their downstream signaling molecules in hematologic malignancies.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
JAKs, STATs and Src kinases in hematopoiesis.
@ast
JAKs, STATs and Src kinases in hematopoiesis.
@en
type
label
JAKs, STATs and Src kinases in hematopoiesis.
@ast
JAKs, STATs and Src kinases in hematopoiesis.
@en
prefLabel
JAKs, STATs and Src kinases in hematopoiesis.
@ast
JAKs, STATs and Src kinases in hematopoiesis.
@en
P2860
P356
P1433
P1476
JAKs, STATs and Src kinases in hematopoiesis.
@en
P2093
E Premkumar Reddy
Sushil G Rane
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205398
P407
P577
2002-05-01T00:00:00Z
P5875
P6179
1007391084