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Arrayed adenoviral expression libraries for functional screening.

Arrayed adenoviral expression libraries for functional screening.

http://www.wikidata.org/entity/Q31112810

about

A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo In situ transduction of target cells on solid surfaces by immobilized viral vectors Toxicity testing in the 21st century: a vision and a strategy Rapid and sensitive lentivirus vector-based conditional gene expression assay to monitor and quantify cell fusion activity The identification of protein kinase C iota as a regulator of the Mammalian heat shock response using functional genomic screens Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway High-efficiency system for the construction of adenovirus vectors and its application to the generation of representative adenovirus-based cDNA expression libraries.Transcriptional-based screens for pathway-specific, high-throughput target discovery in endothelial cells.Induction and characterization of taxol-resistance phenotypes with a transiently expressed artificial transcriptional activator library.Identification of novel mammalian growth regulatory factors by genome-scale quantitative image analysis.shRNA libraries and their use in cancer genetics.A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries An empty E1, E3, E4 adenovirus vector protects photoreceptors from light-induced degeneration Building a human kinase gene repository: bioinformatics, molecular cloning, and functional validation Potential of mesenchymal stem cells in gene therapy approaches for inherited and acquired diseases.Viral-mediated gene delivery for cell-based assays in drug discovery.AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia Functional genomics to new drug targets.The promise of genomics to identify novel therapeutic targets.Wnt-responsive Lgr5-expressing stem cells are hair cell progenitors in the cochlea.Genome-scale functional profiling of the mammalian AP-1 signaling pathway.Genomics and proteomics approaches in understanding tumor angiogenesis.Bioluminescence imaging for assessment and normalization in transfected cell arrays.Gene Delivery by Immobilization to Cell-Adhesive Substrates Vector-based siRNA delivery strategies for high-throughput screening of novel target genes.Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in human primary cells.Improved lipid profile through liver-specific knockdown of liver X receptor alpha in KKAy diabetic mice.Glu(332) in the Nicastrin ectodomain is essential for gamma-secretase complex maturation but not for its activity.An encoded viral micropatch for multiplex cell-based assays through localized gene delivery.Adenoviral vectors expressing siRNAs for discovery and validation of gene function.Profiling the Targets of Protective CD8+ T Cell Responses to Infection.Substrate-mediated delivery from self-assembled monolayers: effect of surface ionization, hydrophilicity, and patterning Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and Nicastrin glycosylation but remain catalytically inactive in the absence of wild type Presenilin.Robust functional gene validation by adenoviral vectors: one-step Escherichia coli-derived recombinant adenoviral genome construction.Contribution of presenilin transmembrane domains 6 and 7 to a water-containing cavity in the gamma-secretase complex.Multiplex cell microarrays for high-throughput screening.Biologically Motivated Approaches to Extrapolation from High to Low Doses and the Advent of Systems Biology: The Road to Toxicological Safety Assessment Current awareness on comparative and functional genomics

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P2860

Arrayed adenoviral expression libraries for functional screening.

http://www.wikidata.org/entity/Q31112810

description

2002 nî lūn-bûn

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2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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Arrayed adenoviral expression libraries for functional screening.

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Arrayed adenoviral expression libraries for functional screening.

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Arrayed adenoviral expression libraries for functional screening.

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Arrayed adenoviral expression libraries for functional screening.

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Nature Biotechnology

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Arrayed adenoviral expression libraries for functional screening.

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Annick Hagers

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Bart Francken

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Christel Schipper

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Ellen Langemeijer

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Evi Narinx

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Filip Beirinckx

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Frits Michiels

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Gert-Jan Arts

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Heidi Pavliska

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Helmuth van Es

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10.1038/NBT746

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11

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20

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