Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B.
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Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiationA quarter century of granzymesGranzyme B cleavage of autoantigens in autoimmunityThe major human and mouse granzymes are structurally and functionally divergentPreclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgarisCurrent and emerging biomarkers of cell death in human disease.Quantitative proteomics and terminomics to elucidate the role of ubiquitination and proteolysis in adaptive immunityGranzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis.The cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics.A translocated bacterial protein protects vascular endothelial cells from apoptosis.Bicaudal is a conserved substrate for Drosophila and mammalian caspases and is essential for cell survivalProteomic profiling of proteases: tools for granzyme degradomics.Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B.Viral cross-class serpin inhibits vascular inflammation and T lymphocyte fratricide; a study in rodent models in vivo and human cell lines in vitro.Role of Bid-induced mitochondrial outer membrane permeabilization in granzyme B-induced apoptosis.Death by a thousand cuts: granzyme pathways of programmed cell deathIntracellular versus extracellular granzyme B in immunity and disease: challenging the dogma.Sequential gene profiling of basal cell carcinomas treated with imiquimod in a placebo-controlled study defines the requirements for tissue rejection.Human and murine granzyme B exhibit divergent substrate preferencesCaspase family proteases and apoptosis.Human NK cell lytic granules and regulation of their exocytosisExecutioner caspase-3 and caspase-7 are functionally distinct proteasesMechanisms of granule-dependent killing.Plasma granzyme B in ST elevation myocardial infarction versus non-ST elevation acute coronary syndrome: comparisons with IL-18 and fractalkineProapoptotic effect and the mechanism of action of pingyangmycin on cavernous hemangiomas.The possible role of granzyme B in the pathogenesis of chronic obstructive pulmonary disease.PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegenerationCurrent advances in the application of proteomics in apoptosis research.Cell death-independent functions of granzymes: hit viruses where it hurts.Dissecting cell death with proteomic scalpels.Caspase-6 as a novel early target in the treatment of Alzheimer's disease.Blessing or curse? Proteomics in granzyme research.Identification of Serpinb6b as a species-specific mouse granzyme A inhibitor suggests functional divergence between human and mouse granzyme A.Real-time detection of CTL function reveals distinct patterns of caspase activation mediated by Fas versus granzyme B.hSMG-1 is a granzyme B-associated stress-responsive protein kinase.The herpes simplex virus type 1 latency-associated transcript can protect neuron-derived C1300 and Neuro2A cells from granzyme B-induced apoptosis and CD8 T-cell killing.Mesenchymal stem cells express serine protease inhibitor to evade the host immune response.Granzyme B-induced cell death exerted by ex vivo CTL: discriminating requirements for cell death and some of its signs.Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs.Hop cleavage and function in granzyme B-induced apoptosis.
P2860
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P2860
Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Molecular ordering of the casp ...... (CTL/NK) protease granzyme B.
@ast
Molecular ordering of the casp ...... (CTL/NK) protease granzyme B.
@en
type
label
Molecular ordering of the casp ...... (CTL/NK) protease granzyme B.
@ast
Molecular ordering of the casp ...... (CTL/NK) protease granzyme B.
@en
prefLabel
Molecular ordering of the casp ...... (CTL/NK) protease granzyme B.
@ast
Molecular ordering of the casp ...... (CTL/NK) protease granzyme B.
@en
P50
P356
P1476
Molecular ordering of the casp ...... (CTL/NK) protease granzyme B.
@en
P304
P356
10.1074/JBC.M410915200
P407
P577
2004-11-29T00:00:00Z