Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
about
Fragmentation of electrospray-produced deprotonated ions of oligodeoxyribonucleotides containing an alkylated or oxidized thymidineFormation and distribution of NNK metabolites in an isolated perfused rat lung.Cytotoxic and mutagenic properties of regioisomeric O²-, N3- and O⁴-ethylthymidines in bacterial cells.Syntheses and characterizations of the in vivo replicative bypass and mutagenic properties of the minor-groove O2-alkylthymidine lesions.Dihydromethysticin from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis and differentially reduces DNA damage in A/J miceCarcinogenicity and DNA adduct formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F-344 rats.The formation and biological significance of N7-guanine adductsPotential contributions of the tobacco nicotine-derived nitrosamine ketone (NNK) in the pathogenesis of steatohepatitis in a chronic plus binge rat model of alcoholic liver diseaseQuantitation of DNA adducts by stable isotope dilution mass spectrometry.Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.Quantitation of pyridyloxobutyl-DNA adducts in tissues of rats treated chronically with (R)- or (S)-N'-nitrosonornicotine (NNN) in a carcinogenicity study.Application of a high-resolution mass-spectrometry-based DNA adductomics approach for identification of DNA adducts in complex mixtures.Context Matters: Contribution of Specific DNA Adducts to the Genotoxic Properties of the Tobacco-Specific Nitrosamine NNK.Liquid chromatography-electrospray ionization-tandem mass spectrometry quantitation of urinary [pyridine-D4]4-hydroxy-4-(3-pyridyl)butanoic acid, a biomarker of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolic activation in smokersReplicative Bypass of O(2)-Alkylthymidine Lesions in Vitro.DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens.Comparative levels of O6-methylguanine, pyridyloxobutyl-, and pyridylhydroxybutyl-DNA adducts in lung and liver of rats treated chronically with the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.Mitochondrial DNA adducts in the lung and liver of F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and (S)-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.Identification of More Than One Hundred Structurally Unique DNA-Phosphate Adducts Formed During Rat Lung Carcinogenesis by the Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone.Pyridylhydroxybutyl and pyridyloxobutyl DNA phosphate adduct formation in rats treated chronically with enantiomers of the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.E-cigarette smoke damages DNA and reduces repair activity in mouse lung, heart, and bladder as well as in human lung and bladder cells.Analysis and Identification of 2'-Deoxyadenosine-Derived Adducts in Lung and Liver DNA of F-344 Rats Treated with the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of its Metabolite 4-(Methylnitrosamino)-
P2860
Q33756812-42F0C686-0032-4B14-91FD-A26FE1648B7EQ33861910-8F4953F6-446C-48BD-A224-59EC9B0A3597Q34096788-F42F9624-CE25-4AE3-90E7-33BB94658D45Q34249731-6E72ACAA-CF16-4A2D-9F54-1167149C0513Q34260237-C8B17B5B-B1FA-4E31-B6B5-A646D1BCF12BQ34586229-0A72B450-2BF6-4599-BD0E-5EDA6E49274CQ34982742-B0FC769D-4DDD-4CD5-BED6-C40EEBC16BD0Q35081538-0FE9D0F1-9EC8-4887-9F5B-A2D8BC1B73DBQ36390390-2A26F4C9-0A21-4CEE-9F5D-0B0959D0982DQ37240535-48508B9A-0B35-455A-AFED-DA8DB62E0312Q37358769-02A6B951-8F9B-4756-BEC1-1901C2AB7370Q37696819-53C71808-7EF1-4597-A381-0CDAC276DF2DQ39090703-BEB6B163-99FB-46D6-946F-A4A9EB6C1AC0Q39148132-9FDD209C-B89D-4F63-8905-93483F6C1F95Q39407326-F7268AD0-B763-4F8E-9278-17CBB9B6C6B2Q40003876-95BD2DC5-5647-41FE-BFA9-863D1B705A09Q43125361-E8B282D8-8473-4C6D-B12E-280AA1F72B70Q43151741-FAAA8FBD-39BC-4F6D-A344-5A33F74197F7Q47607301-4DAC9DAA-8BD6-4F86-A9D0-67C34E947328Q47773951-4E63C352-355C-4930-8CC9-8EC12EA3CD08Q47777080-8D209B3A-190E-4900-AC62-9CE0ADD95A84Q49596707-47C2E09E-B18D-4550-9F53-E216561510D8Q53176118-C7384D07-5CED-4AF9-A208-54FB41CCF7E1
P2860
Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Quantitation of pyridylhydroxy ...... mino)-1-(3-pyridyl)-1-butanol.
@ast
Quantitation of pyridylhydroxy ...... mino)-1-(3-pyridyl)-1-butanol.
@en
type
label
Quantitation of pyridylhydroxy ...... mino)-1-(3-pyridyl)-1-butanol.
@ast
Quantitation of pyridylhydroxy ...... mino)-1-(3-pyridyl)-1-butanol.
@en
prefLabel
Quantitation of pyridylhydroxy ...... mino)-1-(3-pyridyl)-1-butanol.
@ast
Quantitation of pyridylhydroxy ...... mino)-1-(3-pyridyl)-1-butanol.
@en
P2093
P2860
P356
P1476
Quantitation of pyridylhydroxy ...... mino)-1-(3-pyridyl)-1-butanol.
@en
P2093
J Bradley Hochalter
Peter W Villalta
Pramod Upadhyaya
Stephen Kalscheuer
Stephen S Hecht
P2860
P304
P356
10.1021/TX8001109
P577
2008-06-21T00:00:00Z