Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells
about
Cannabis and tobacco smoke are not equally carcinogenic.Nicotine exposure and bronchial epithelial cell nicotinic acetylcholine receptor expression in the pathogenesis of lung cancerGenetic susceptibility to lung cancer and co-morbiditiesImmune evasion by murine melanoma mediated through CC chemokine receptor-10Nicotine signals through muscle-type and neuronal nicotinic acetylcholine receptors in both human bronchial epithelial cells and airway fibroblastsEffects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathioneIncreased staining for phospho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsiesThe Oncogenic Functions of Nicotinic Acetylcholine ReceptorsRole of α7 nicotinic receptor in the immune system and intracellular signaling pathwaysRole of acetylcholinesterase in lung cancerBcl2 Family Functions as Signaling Target in Nicotine-/NNK-Induced Survival of Human Lung Cancer Cells.Will chronic e-cigarette use cause lung disease?Survival function of protein kinase C{iota} as a novel nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-activated bad kinaseChromium genotoxicity: A double-edged swordPoly(ester amine)-mediated, aerosol-delivered Akt1 small interfering RNA suppresses lung tumorigenesisChemoprevention of lung cancer: prospects and disappointments in human clinical trialsNicotine-mediated cell proliferation and tumor progression in smoking-related cancersLung injury, inflammation and Akt signaling following inhalation of particulate hexavalent chromiumComputer-aided targeting of the PI3K/Akt/mTOR pathway: toxicity reduction and therapeutic opportunitiesRole of chaperone mediated autophagy (CMA) in the degradation of misfolded N-CoR protein in non-small cell lung cancer (NSCLC) cellsCigarette smoke promotes drug resistance and expansion of cancer stem cell-like side populationPersistent nicotine treatment potentiates amplification of the dihydrofolate reductase gene in rat lung epithelial cells as a consequence of Ras activationQuantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.Should the health community promote smokeless tobacco (snus) as a harm reduction measure?A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis.Synergistic effect of ERK inhibition on tetrandrine-induced apoptosis in A549 human lung carcinoma cells.Lung carcinoma signaling pathways activated by smoking.The role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesis.The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients.Nicotine-mediated signals modulate cell death and survival of T lymphocytes.ASCL1 regulates the expression of the CHRNA5/A3/B4 lung cancer susceptibility locus.Overexpression and activation of the alpha9-nicotinic receptor during tumorigenesis in human breast epithelial cells.NeuroD1 mediates nicotine-induced migration and invasion via regulation of the nicotinic acetylcholine receptor subunits in a subset of neural and neuroendocrine carcinomas.Effects of cigarette smoke on the human oral mucosal transcriptomeHigh level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886)Crosstalk between nicotine and estrogen-induced estrogen receptor activation induces α9-nicotinic acetylcholine receptor expression in human breast cancer cells.Development of novel approach to diagnostic imaging of lung cancer with 18F-Nifene PET/CT using A/J mice treated with NNK.Aberrant DNA methylation links cancer susceptibility locus 15q25.1 to apoptotic regulation and lung cancer.Mechanisms of Cancer Induction by Tobacco-Specific NNK and NNN.Activated cholinergic signaling provides a target in squamous cell lung carcinoma.
P2860
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P2860
Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Rapid Akt activation by nicoti ...... human airway epithelial cells
@ast
Rapid Akt activation by nicoti ...... human airway epithelial cells
@en
Rapid Akt activation by nicoti ...... human airway epithelial cells
@nl
type
label
Rapid Akt activation by nicoti ...... human airway epithelial cells
@ast
Rapid Akt activation by nicoti ...... human airway epithelial cells
@en
Rapid Akt activation by nicoti ...... human airway epithelial cells
@nl
prefLabel
Rapid Akt activation by nicoti ...... human airway epithelial cells
@ast
Rapid Akt activation by nicoti ...... human airway epithelial cells
@en
Rapid Akt activation by nicoti ...... human airway epithelial cells
@nl
P2093
P2860
P3181
P1476
Rapid Akt activation by nicoti ...... human airway epithelial cells
@en
P2093
Amy S Clark
Curtis Harris
Ilona R Linnoila
John Brognard
Kip A West
Phillip A Dennis
Steven Belinsky
Xiaowei Yang
P2860
P3181
P356
10.1172/JCI16147
10.1172/JCI200316147
P407
P577
2003-01-01T00:00:00Z