about
Obesity, Inflammation, and Insulin ResistanceFatty acid metabolism and the basis of brown adipose tissue functionMitochondrial fatty acid oxidation in obesityAdenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: effects on cell metabolism and insulin secretionCeramides and mitochondrial fatty acid oxidation in obesity.Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.Brown Adipose Tissue Bioenergetics: A New Methodological ApproachInflammation and adipose tissue macrophages in lipodystrophic mice.Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profileAltered circadian rhythm and metabolic gene profile in rats subjected to advanced light phase shifts.Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition.Carnitine Palmitoyltransferase 1 Increases Lipolysis, UCP1 Protein Expression and Mitochondrial Activity in Brown Adipocytes.(-)-UB006: A new fatty acid synthase inhibitor and cytotoxic agent without anorexic side effects.Carnitine palmitoyltransferase 1C: From cognition to cancer.Hypothalamic regulation of liver and muscle nutrient partitioning by brain-specific carnitine palmitoyltransferase 1C (CPT1C) in male mice.Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity.CPT I overexpression protects L6E9 muscle cells from fatty acid-induced insulin resistance.Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation.Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes.Short-term vitamin E treatment impairs reactive oxygen species signaling required for adipose tissue expansion, resulting in fatty liver and insulin resistance in obese mice.The transcription factor SREBP-1c is instrumental in the development of beta-cell dysfunction.C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight.Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes.HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism.Increased inflammation, oxidative stress and mitochondrial respiration in brown adipose tissue from obese mice.Ghrelin Causes a Decline in GABA Release by Reducing Fatty Acid Oxidation in Cortex.Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation.Enhancing hepatic fatty acid oxidation as a strategy for reversing metabolic disorders programmed by maternal undernutrition during gestation.New approaches targeting brown adipose tissue transplantation as a therapy in obesityVitamin E reduces adipose tissue fibrosis, inflammation, and oxidative stress and improves metabolic profile in obesityCPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity.Impact of Adaptive Thermogenesis in Mice on the Treatment of ObesityTargeting AgRP neurons to maintain energy balance: Lessons from animal models
P50
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P50
description
hulumtuese
@sq
onderzoeker
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researcher
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ricercatrice
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հետազոտող
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name
Laura Herrero
@ast
Laura Herrero
@en
Laura Herrero
@es
Laura Herrero
@nl
Laura Herrero
@sl
type
label
Laura Herrero
@ast
Laura Herrero
@en
Laura Herrero
@es
Laura Herrero
@nl
Laura Herrero
@sl
prefLabel
Laura Herrero
@ast
Laura Herrero
@en
Laura Herrero
@es
Laura Herrero
@nl
Laura Herrero
@sl
P214
P1053
D-4011-2014
P106
P1580
P21
P214
P31
P3829
P496
0000-0003-4244-4673
P735
P7859
viaf-305878879