Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
about
Mitochondrial fatty acid oxidation in obesityDefinition by functional and structural analysis of two malonyl-CoA sites in carnitine palmitoyltransferase 1AAccD6, a member of the Fas II locus, is a functional carboxyltransferase subunit of the acyl-coenzyme A carboxylase in Mycobacterium tuberculosisIncreasing fatty acid oxidation remodels the hypothalamic neurometabolome to mitigate stress and inflammation4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid (C75), an inhibitor of fatty-acid synthase, suppresses the mitochondrial fatty acid synthesis pathway and impairs mitochondrial functionInhibitors of Fatty Acid Synthesis Induce PPAR α -Regulated Fatty Acid β -Oxidative Genes: Synergistic Roles of L-FABP and GlucoseThe mitochondrial H(+)-ATP synthase and the lipogenic switch: new core components of metabolic reprogramming in induced pluripotent stem (iPS) cells.Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity.Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight.Inhibition of L-carnitine biosynthesis and transport by methyl-γ-butyrobetaine decreases fatty acid oxidation and protects against myocardial infarction.Differential in radiosensitizing potency of enantiomers of the fatty acid synthase inhibitor C75.HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism.Alterations to mitochondrial fatty-acid use in skeletal muscle after chronic exposure to hypoxia depend on metabolic phenotype.Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer.Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis
P2860
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P2860
Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
description
2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
@ast
Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
@en
type
label
Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
@ast
Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
@en
prefLabel
Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
@ast
Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
@en
P2093
P50
P356
P1433
P1476
Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
@en
P2093
Assia Bentebibel
David Sebastián
Eduardo López-Viñas
Fausto G Hegardt
Guillermina Asins
P304
P356
10.1021/BI052186Q
P407
P577
2006-04-01T00:00:00Z