Urinary metabolites of a novel quinoxaline non-nucleoside reverse transcriptase inhibitor in rabbit, mouse and human: identification of fluorine NIH shift metabolites using NMR and tandem MS.
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The challenges of in silico contributions to drug metabolism in lead optimization.The role of fluorine in medicinal chemistry.Fluorine in medicinal chemistry.Metabolism, excretion, and mass balance of the HIV-1 integrase inhibitor dolutegravir in humansApproaches for the rapid identification of drug metabolites in early clinical studies.Formation of a defluorinated metabolite of a quinoxaline antiviral drug catalysed by human cytochrome P450 1A2.N-O glucuronidation: a major human metabolic pathway in the elimination of two novel anti-convulsant drug candidates.Metabolism of a novel nucleoside analogue, OGT 719, in the isolated perfused rat liver model, in rats, in tumour models and in patients.Addressing the challenge of limited sample volumes inin vitrostudies with capillary-scale microfluidic LC–MS/MS
P2860
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P2860
Urinary metabolites of a novel quinoxaline non-nucleoside reverse transcriptase inhibitor in rabbit, mouse and human: identification of fluorine NIH shift metabolites using NMR and tandem MS.
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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name
Urinary metabolites of a novel ...... lites using NMR and tandem MS.
@ast
Urinary metabolites of a novel ...... lites using NMR and tandem MS.
@en
type
label
Urinary metabolites of a novel ...... lites using NMR and tandem MS.
@ast
Urinary metabolites of a novel ...... lites using NMR and tandem MS.
@en
prefLabel
Urinary metabolites of a novel ...... lites using NMR and tandem MS.
@ast
Urinary metabolites of a novel ...... lites using NMR and tandem MS.
@en
P2093
P2860
P356
P1433
P1476
Urinary metabolites of a novel ...... lites using NMR and tandem MS.
@en
P2093
P2860
P304
P356
10.1080/004982500237604
P407
P577
2000-04-01T00:00:00Z