Human placenta sphingomyelinase, an exogenous acidic pH-optimum sphingomyelinase, induces oxidative stress, glutathione depletion, and apoptosis in rat hepatocytes.
about
Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alphaDefective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice.Probiotic sonicates selectively induce mucosal immune cells apoptosis through ceramide generation via neutral sphingomyelinaseSpecific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.Sphingomyelinase stimulates oxidant signaling to weaken skeletal muscle and promote fatigue.Glutathione depletion impairs myogenic differentiation of murine skeletal muscle C2C12 cells through sustained NF-kappaB activationAcid Sphingomyelinase Mediates Oxidized-LDL Induced Apoptosis in Macrophage via Endoplasmic Reticulum Stress.Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus.Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis.Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitisVitamin E prevents the age-dependent and palmitate-induced disturbances of sphingolipid turnover in liver cellsASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism.The Role of Ceramide in the Pathogenesis of Alcoholic Liver Disease.Ceramide-induced G2 arrest in rhabdomyosarcoma (RMS) cells requires p21Cip1/Waf1 induction and is prevented by MDM2 overexpression.Cytotoxic 3,5-bis(benzylidene)piperidin-4-ones and N-acyl analogs displaying selective toxicity for malignant cells.Role of ceramide in Ca2+-sensing receptor-induced apoptosis.Cyclic GMP-dependent inhibition of acid sphingomyelinase by nitric oxide: an early step in protection against apoptosis.Increased secretory sphingomyelinase activity in the first trimester of pregnancy in women later developing preeclampsia: a nested case-control study.Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine LiverInvolvement of ceramide in the mechanism of Cr(VI)-induced apoptosis of CHO cells.The relation between sphingomyelinase activity, lipid peroxide oxidation and NO-releasing in mice liver and brain.Neutral sphingomyelinase-induced ceramide triggers germinal vesicle breakdown and oxidant-dependent apoptosis in Xenopus laevis oocytes.The role of sphingolipids in psychoactive drug use and addiction.
P2860
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P2860
Human placenta sphingomyelinase, an exogenous acidic pH-optimum sphingomyelinase, induces oxidative stress, glutathione depletion, and apoptosis in rat hepatocytes.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
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2000年論文
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2000年论文
@wuu
name
Human placenta sphingomyelinas ...... apoptosis in rat hepatocytes.
@ast
Human placenta sphingomyelinas ...... apoptosis in rat hepatocytes.
@en
type
label
Human placenta sphingomyelinas ...... apoptosis in rat hepatocytes.
@ast
Human placenta sphingomyelinas ...... apoptosis in rat hepatocytes.
@en
prefLabel
Human placenta sphingomyelinas ...... apoptosis in rat hepatocytes.
@ast
Human placenta sphingomyelinas ...... apoptosis in rat hepatocytes.
@en
P2093
P356
P1433
P1476
Human placenta sphingomyelinas ...... apoptosis in rat hepatocytes.
@en
P2093
Fernández-Checa JC
García-Ruiz C
P356
10.1053/JHEP.2000.8267
P407
P577
2000-07-01T00:00:00Z