Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism.
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Identification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasionCovalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition ReactionsCLEFMA-an anti-proliferative curcuminoid from structure-activity relationship studies on 3,5-bis(benzylidene)-4-piperidones.Liver S9 Fraction-Derived Metabolites of Curcumin Analogue UBS109.Autophagy and apoptosis in hepatocellular carcinoma induced by EF25-(GSH)2: a novel curcumin analog.Mouse pharmacokinetics and metabolism of the curcumin analog, 4-piperidinone,3,5-bis[(2-fluorophenyl)methylene]-acetate(3E,5E) (EF-24; NSC 716993).Anticancer activity of an imageable curcuminoid 1-[2-aminoethyl-(6-hydrazinopyridine-3-carbamidyl)-3,5-bis-(2-fluorobenzylidene)-4-piperidone (EFAH)Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties.A new multicolor bioluminescence imaging platform to investigate NF-κB activity and apoptosis in human breast cancer cells.Alkyl Cinnamates Induce Protein Kinase C Translocation and Anticancer Activity against Breast Cancer Cells through Induction of the Mitochondrial Pathway of Apoptosis.Monocarbonyl curcumin analogues: heterocyclic pleiotropic kinase inhibitors that mediate anticancer properties.The effects of turmeric (curcumin) on tumor suppressor protein (p53) and estrogen receptor (ERα) in breast cancer cells.HDAC inhibitors, MS-275 and salermide, potentiates the anticancer effect of EF24 in human pancreatic cancer cells.Curcumin analog UBS109 prevents bone marrow osteoblastogenesis and osteoclastogenesis disordered by coculture with breast cancer MDA-MB-231 bone metastatic cells in vitro.EF24 and RAD001 potentiates the anticancer effect of platinum-based agents in human malignant pleural mesothelioma (MSTO-211H) cells and protects nonmalignant mesothelial (MET-5A) cells.KSRP/FUBP2 Is a Binding Protein of GO-Y086, a Cytotoxic Curcumin Analogue.A DNA methyltransferase modulator inspired by peyssonenyne natural product structures.Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition.Design and synthesis of novel iminothiazinylbutadienols and divinylpyrimidinethiones as ARE inducers.Apoptosis Induced by the Curcumin Analogue EF-24 Is Neither Mediated by Oxidative Stress-Related Mechanisms nor Affected by Expression of Main Drug Transporters ABCB1 and ABCG2 in Human Leukemia Cells.Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3
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Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 October 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Curcumin analog cytotoxicity a ...... f a redox-dependent mechanism.
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Curcumin analog cytotoxicity a ...... f a redox-dependent mechanism.
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type
label
Curcumin analog cytotoxicity a ...... f a redox-dependent mechanism.
@en
Curcumin analog cytotoxicity a ...... f a redox-dependent mechanism.
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prefLabel
Curcumin analog cytotoxicity a ...... f a redox-dependent mechanism.
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Curcumin analog cytotoxicity a ...... f a redox-dependent mechanism.
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P2093
P2860
P1476
Curcumin analog cytotoxicity a ...... f a redox-dependent mechanism.
@en
P2093
Aiming Sun
Dennis C Liotta
Haipeng Hu
James P Snyder
Mamoru Shoji
P2860
P304
P356
10.1016/J.BMCL.2009.10.023
P407
P577
2009-10-08T00:00:00Z